Results 101 to 110 of about 1,736,727 (289)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Exact Solutions in Poincaré Gauge Gravity Theory

open access: yesUniverse, 2019
In the framework of the gauge theory based on the Poincaré symmetry group, the gravitational field is described in terms of the coframe and the local Lorentz connection. Considered as gauge field potentials, they give rise to the corresponding field
Yuri N. Obukhov
doaj   +1 more source

Exact solutions of effective-mass Schrodinger equations

open access: yes, 2002
We outline a general method for obtaining exact solutions of Schr\"{o}dinger equations with a position dependent effective mass and compare the results with those obtained within the frame of supersymmetric quantum theory.
BEŞIRE GÖNÜL   +6 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Exact solutions of 2d supersymmetric gauge theories

open access: yesJournal of High Energy Physics, 2019
We study dynamics of two-dimensional non-abelian gauge theories with N $$ \mathcal{N} $$ = (0, 2) supersymmetry that include N $$ \mathcal{N} $$ = (0, 2) supersymmetric QCD and its generaliza- tions.
Abhijit Gadde   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

ABOUT EXACT SOLUTIONS OF MEASUREMENT'S INVERSE PROBLEMS

open access: yesVìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Modelûvannâ, 2013
The inverse problems of measurement are investigated in this paper. The mainhypothesis was suggested for estimation from below of exact solutions of suchproblems. Two practical inverse problems have been considered as examples: inverse problem of Krylov,
Yu. L. Menshikov
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Supersymmetric Ito equation: Bosonization and exact solutions

open access: yesAIP Advances, 2013
Based on the bosonization approach, the N=1 supersymmetric Ito (sIto) system is changed to a system of coupled bosonic equations. The approach can effectively avoid difficulties caused by intractable fermionic fields which are anticommuting.
Bo Ren, Ji Lin, Jun Yu
doaj   +1 more source

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