Results 111 to 120 of about 3,701,157 (303)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Exact Solutions in Poincaré Gauge Gravity Theory
Universe, 2019 In the framework of the gauge theory based on the Poincaré symmetry group, the gravitational field is described in terms of the coframe and the local Lorentz connection. Considered as gauge field potentials, they give rise to the corresponding field
Yuri N. Obukhov
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Exact solutions of 2d supersymmetric gauge theories
Journal of High Energy Physics, 2019 We study dynamics of two-dimensional non-abelian gauge theories with N $$ \mathcal{N} $$ = (0, 2) supersymmetry that include N $$ \mathcal{N} $$ = (0, 2) supersymmetric QCD and its generaliza- tions.
Abhijit Gadde +2 more
doaj +1 more source
Exact Solutions of Nonlinear Partial Differential Equations
, 2010 M.Sc. ( Mathematics and Computing)The thesis entitled “ EXACT SOLUTIONS OF NONLINEAR PARTIAL DIFFRENTIAL EQUATIONS ” is an attempt to obtain the exact solutions of some nonlinear partial differential equations ...
Singla, Shivali
core
, 2010 Two analytical techniques for the generation of wide classes of exact solutions of the nonlinear Schrödinger equation (NLSE) containing an external potential are proposed.
B. A. Malomed +3 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
ABOUT EXACT SOLUTIONS OF MEASUREMENT'S INVERSE PROBLEMS
Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Modelûvannâ, 2013 The inverse problems of measurement are investigated in this paper. The mainhypothesis was suggested for estimation from below of exact solutions of suchproblems. Two practical inverse problems have been considered as examples: inverse problem of Krylov,
Yu. L. Menshikov
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source