Results 91 to 100 of about 325,651 (334)
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
Simulating pseudotruss excavating part of excavators
Vestnik MGSU, 2019 Introduction. Single-dipper hydraulic excavators are becoming widely used multifunctional machines. Upgrading the machine as a whole and its assemblies is an actual problem to be solved with the aim of reducing material consumption and increasing stability and throughput.
Oleg A. Zotov, Dmitriy Yu. Gustov
openaire +2 more sources
Advanced Science, EarlyView.Compared with those on the pTi surface, macrophages on the TNTs surface present reduced myosin II contractility, which facilitates the nuclear translocation of the UTX. This reduction decreases the enrichment of the repressive H3K27me3 histone modification at the Abca1 gene locus, which promotes the transcription and protein expression of ABCA1 ...
Hengji Jia +8 more
wiley +1 more source
Forensic excavations and burials in Uruguay, 2004–10
Human Remains and Violence, 2016 This article will describe the contemporary scientific techniques used to excavate and identify the dead bodies of disappeared detainees from the Uruguayan dictatorship.
Jose López Mazz
doaj +1 more source
Estrategias de excavación y datación de arquitectura pública temprana. El caso de Cerro Lampay
Bulletin de l'Institut Français d'Études Andines, 2008 The design of excavations at Cerro Lampay, as well as the strategy to recover organic samples for 14C analysis are presented in detail, noting the potentialities of a methodology where field options are closely linked with clear-cut and specific research
Rafael Vega-Centeno Sara-Lafosse
doaj +1 more source
Effect of consolidation on the behaviour of excavations in fine-grained soils [PDF]
, 2016 This study deals with the detrimental effects of consolidation on the behaviour of excavations carried out in fine-grained soils. With the aim of reproducing the main aspects of the mechanical behaviour of medium-soft clays, an advanced constitutive ...
Bertoldo, Fabiano, Callisto, Luigi
core +1 more source
Advanced Science, EarlyView.Overcoming platinum resistance in high‐grade serous ovarian cancer (HGSOC) is critical for improving outcomes. This study identifies lncRNA CATED, elevated in platinum‐resistant small extracellular vesicles (sEVs) and tumors, which drives cisplatin resistance by enhancing DHX36 SUMOylation, boosting RAP1A translation, and activating MAPK signaling ...
Yi Liu +7 more
wiley +1 more source
Wide Linearity Range and Rapid‐Response Tactile Sensor Inspired by Parallel Structures
Advanced Science, EarlyView.Inspired by parallel structures, a composite tactile sensor design is proposed using parallel elastomer integration, developing two novel sensors. This strategy optimizes the force‐electric response and viscoelastic hysteresis of the conductive composite, achieving a balanced enhancement of linear sensing range and fast response.
Weihua Gao +7 more
wiley +1 more source
Angewandte Chemie, EarlyView.To monitor small molecule‐induced changes in protein polyubiquitination in an unbiased manner, we employ enrichment through tandem ubiquitin binding entities coupled to LC‐MS/MS analysis (TUBE‐MS). By applying the workflow to PROTAC, p97‐ and deubiquitinase‐inhibitor treatment of cells, we demonstrate its broad applicability and reveal the induction of
Siska Führer +6 more
wiley +2 more sources