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Inspirational Teaching: Beyond Excellence and Towards Collaboration for Learning with Sustained Impact [PDF]
, 2014 Within higher education, there is a continued focus on teaching quality, with teaching excellence often linked to the idea of engaging and motivating students.
Jensen, Kathrine +5 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
12th Excellence in Pediatrics Conference – 2020 Book of Abstracts
Cogent Medicine, 2020 Excellence in Pediatrics
doaj +1 more source
Achieving excellence in construction
The UK construction industry at its best is excellent. Nonetheless there is a deep concern that the industry as a whole is underachieving. Problems such as low and unreliable profitability, a lack of research and development, a shortage of skills ...
Amaratunga, Dilanthi +2 more
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Center for Teaching Excellence Fall 2019 Newsletter
, 2019 Inside this issue: Upcoming Events -- New Chair of the Faculty Fellows -- The CTE Teaching & Innovation Colloquy -- Save the Date: 7th Annual Symposium on Teaching and Learning -- Who We Are -- Thank you, Josh!
Center for Teaching Excellence
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Excellence in Agronomy is a CGIAR-wide initiative that seeks to accelerate the uptake of validated agronomic solutions at scale. Our vision is smallholder farming that is on a path towards sustainable intensification and climate change adaptation.
CGIAR Initiative on Excellence in Agronomy
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