Results 81 to 90 of about 1,916,060 (298)
For modern global economic activity changes in the structureof goods, networks, technical and technological developmentand increased competence are significant, which requiresnew solutions and new mode of thinking.The competitive model which relied in ...
Igor Trupac, Jurij Kolenc, Stipan Matoš
doaj +1 more source
Conceptions of excellence in teaching and learning and implications for future policy and practice [PDF]
Within a diverse and expanding system of higher education (HE), such as in the UK, discourse on teaching and student learning highlights tensions between different notions of excellence.
Little, Brenda, Locke, William
core
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Understanding the Widespread Applicability of Transformative Leadership
For too long, schools and other organizations have relied on what have come to be known as technical, rational, or functional approaches to leadership, stemming in the global north, from scientific management in the early 20th century.
Carolyn Muriel Shields
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Lecturers as educators have a very large role in determining the quality of higher education graduates. Transformational leadership becomes a leadership style that can be used by lecturers to direct and guide students to have superior character ...
Meditatio Situmorang +1 more
doaj
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
CGIAR Excellence in Breeding Platform - Plan of Work and Budget 2020 [PDF]
At the end of 2019, all CGIAR centers had submitted improvement plans based on an EiB template and in close collaboration with EiB staff while – in a parallel process with breeding programs, funders and private sector representatives – a vision for ...
CGIAR Excellence in Breeding Platform
core
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source

