Results 111 to 120 of about 2,067,379 (337)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The Macroeconomics of Loss of Fulltime Student Status or the Fiscal Consequences of Passing or Not Passing an Exam [PDF]
Financial Theory and Practice, 2009 This article is the first systematic attempt at an overview of the extent of fiscal and non-fiscal support to students in Croatia, taking University of Split as an example.
Petar Filipić
doaj
Knowledge Management Maturity in Universities and its Impact on Performance Excellence "Comparative study" [PDF]
, 2016 The paper assesses Knowledge Management Maturity(KMM) in the universities to determine the impact of knowledge management on performance excellence. This study was applied on Al-Azhar University and Al-Quds Open University in Gaza strip, Palestine.
Abu Amuna, Youssef M. +2 more
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
One Jefferson News October 2017 [PDF]
, 2017 Over the past month, we have continued our One Jefferson journey and achieved a number of integration successes for the organization as well as our patient and student communities.
Performance Excellence,
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
One Jefferson News September 2017 [PDF]
, 2017 Over the past three years, we have embarked on an exciting journey of reimagining a new model for health and education to create One Jefferson. Our first step was to bring together Thomas Jefferson University and Thomas Jefferson University Hospital.
Performance Excellence,
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
A strategic approach to the implementation of new technologies in the media [PDF]
Ekonomija: teorija i praksa, 2015 In conditions of rapid technological changes and ongoing introduction of new technologies in the media, we need to continuously work on the timely adjustment of human resources to new challenges.
Jašarević Faruk, Kuka Ermin
doaj
Organizational Excellence in Palestinian Universities of Gaza Strip [PDF]
, 2017 The research aims to identify the organizational excellence in Palestinian universities of Gaza Strip, from the perspective of senior management. The questionnaires were distributed the top senior management in the Palestinian universities, and the study
Abu-Naser, Samy S. +3 more
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