Results 101 to 110 of about 47,744 (298)
European Journal of Turkish Studies, 2012 A proper analysis of the Events of 6/7 September requires taking into account the ethnic and religious homogenization practices of the Kemalist elite, the exceptional of democratic and financial circumstances of the 1950s and the Cyprus conflict ...
Dilek Güven
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
I limiti all’amnistia nel sistema penale italiano [PDF]
Democrazia e Diritti Sociali, 2018 Issues regarding the main characteristics of amnesty in the Italian legal system are analysed with specific reference to the relationship between amnesty and the purposes of punishment.
Massimo Luigi Ferrante
doaj
آليات الحماية الدولية والوطنية المعنية بحقوق الإنسان في الظروف الاستثنائية / International And National Protection Mechanisms Concerning Human Rights In Exceptional Circumstances [PDF]
مجلة الشريعة والقانون بالقاهرةيتناول هذا البحث دراسة تحليلية لآليات حماية حقوق الإنسان وحرياته الأساسية في ظل الظروف الاستثنائية، ولا سيما حالات الطوارئ التي كثيرًا ما تقترن، في الواقع العملي الدولي، بانتهاكات بالغة الخطورة لهذه الحقوق نتيجة التوسع في سلطات الدولة وضعف الضمانات ...
هديل محمود جمال الدين زغلول إبراهيم
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2008 The Australian Government commissioned the Bureau of Meteorology and the Commonwealth Scientific and Industrial Research Organisation (CSIRO) to undertake a climatic assessment of the likely future climate patterns and the current Exceptional ...
core
الجزاءات الإدارية "دراسة تحليلية مقارنة" [PDF]
Al-Maǧallah Al-Qānūniyyaẗيتناول هذا البحث دراسة الجزاءات الإدارية بوصفها أحد بدائل العقوبات الجنائية توقعها جهة الإدارة على المخالفين من الأفراد والمؤسسات في غير مجالي التأديب والعقود الإدارية بمقتضى قرارات إدارية ذات طابع جزائي، بهدف الحد من تدخل القانون الجنائي وعدم ملاءمة ...
فرج سالم محمد الأوجلي
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Income Contingent Loans for Drought Relief: Delivering better outcomes for farmers and taxpayers [PDF]
Australia’s National Drought Policy is considered to be one of the most advanced in the world, recognising as it does the reality of climate and focusing on adapting farm management to climatic uncertainty rather than simply subsidising agriculture in ...
Linda C. Botterill, Bruce Chapman
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source