Results 51 to 60 of about 149,354 (217)

Al-Firaa Scholar's Method in the Exceptional Readings: Critical Study

open access: yesمجلة الآداب, 2018
Through discussion and analysis, the research tackles Al-Firaa's stance towards the Quranic exceptional readings by searching the practical highlights which his book "Maani Al-Quran" included. The research also discusses Al-Firaa's regulations through an
ضياء حسين حميد الموسويّ
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Aesthetic experience and the emotional content of paintings [PDF]

open access: yesPsihologija, 2010
In this study we investigated the relationship between aesthetic experience and other emotional qualities judged in paintings. Aesthetic experience was defined as an exceptional state of mind in which a person is focused on a particular object ...
Slobodan Marković
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An Inductive Logical Model with Exceptional Information for Error Detection and Correction in Large Knowledge Bases

open access: yesMathematics
Some knowledge bases (KBs) extracted from Wikipedia articles can achieve very high average precision values (over 95% in DBpedia). However, subtle mistakes including inconsistencies, outliers, and erroneous relations are usually ignored in the ...
Yan Wu   +3 more
doaj   +1 more source

Distance Bounds for Graphs with Some Negative Bakry-Émery Curvature

open access: yesAnalysis and Geometry in Metric Spaces, 2019
We prove distance bounds for graphs possessing positive Bakry-Émery curvature apart from an exceptional set, where the curvature is allowed to be non-positive.
Liu Shiping   +3 more
doaj   +1 more source

Comparison of researchers' impact indices.

open access: yesPLoS ONE, 2020
Researchers contribute to the frontiers of knowledge by establishing facts and reaching new conclusions through systematic investigations, and by subsequently publishing the outcomes of their research findings in the form of research papers.
Samreen Ayaz, Nayyer Masood
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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