Results 61 to 70 of about 149,354 (217)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Lebesgue points for functions from generalized Sobolev classes Mpa(X) in the critical case

open access: yesЖурнал Белорусского государственного университета: Математика, информатика, 2019
Classical Lebesgue theorem states that for any integrable function almost every point (except the set of measure zero)  is a Lebesgue point. The set of the points that are not Lebesgue points is called an exceptional set.
Sergey A. Bondarev
doaj  

Spatial counterfactuals to explore disastrous flooding

open access: yesEnvironmental Research Letters
Flood-prone people and decision-makers are often unwilling to discuss and prepare for exceptional events, as such events are hard to perceive and out of experience for most people. Once an exceptional flood occurs, affected people and decision-makers are
Bruno Merz   +8 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Thematic linking in Hausa asymmetric coordination

open access: yesStudies in African Linguistics, 1989
This paper investigates "asymmetric coordination" in Nigerian Hausa. A range of constructions is presented in which asymmetric coordination occurs, and their syntactic and semantic properties are established.
Linda Schwartz
doaj   +3 more sources

Infinite and finite consistent truncations on deformed generalised parallelisations

open access: yesJournal of High Energy Physics
Given a manifold M $$ \mathbbm{M} $$ admitting a maximally supersymmetric consistent truncation, we show how to formulate new consistent truncations by restricting to a set of Kaluza-Klein modes on M $$ \mathbbm{M} $$ invariant under some subgroup of the
Chris D. A. Blair   +2 more
doaj   +1 more source

The questions of the operation of law in time while overcoming the gaps in legislation

open access: yesТеорія і практика правознавства, 2016
The article analyses the ways of retention of the time parameters set for a particular legal norm while application of the latter for overcoming the gaps in legislation.
О. В. Пушняк
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Hölder Quasicontinuity in Variable Exponent Sobolev Spaces

open access: yesJournal of Inequalities and Applications, 2007
We show that a function in the variable exponent Sobolev spaces coincides with a Hölder continuous Sobolev function outside a small exceptional set.
Kinnunen Juha   +2 more
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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