Results 81 to 90 of about 6,078,017 (281)

Heat shock transcription factor 1 preserves cardiac angiogenesis and adaptation during pressure overload [PDF]

open access: yes, 2008
To examine how heat shock transcription factor 1 (HSF1) protects against maladaptive hypertrophy during pressure overload, we subjected HSF1 transgenic (TG), knockout (KO) and wild type (WT) mice to a constriction of transverse aorta (TAC), and found ...
Yuqi Wang   +16 more
core  

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Experimental verification of suitability of insulation testing rig in determining thermophysical properties of insulating materials

open access: yesCogent Engineering, 2019
Verification of suitability of insulation testing rig (ITR) in determining the thermophysical properties of insulating materials (IM) is strongly based on the measurement of temperatures on the inner/outer surfaces of the insulators (white cotton fabric,
S. N. Nnamchi   +4 more
doaj   +1 more source

Condensing Heat Exchangers Optimize Steam Boilers

open access: yes, 1983
The development of fluorocarbon resin covered tubes has advanced to the point where full scale marketing in connection with condensing heat exchangers has begun. Field installations show simple paybacks of one to one and a half years with resulting steam
Sullivan, B., Sullivan, P. A.
core  

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

Influence of initial binary mixture state of matter on heat costs at rectification

open access: yesТонкие химические технологии, 2014
Analysis of heat cost for rectification was performed taking into account the phase state of the original mixture. It was proved theoretically that increasing feed vapor fraction leads to decreasing energy consumption in conventional distillation process.
M. K. Zakharov, Mohand Abbasi
doaj  

Characterizing adaptive capacity for the future heat-related cardiovascular morbidity burden in U.S. Metropolitan areas

open access: yesEnvironment International
Exposure to excess heat is linked to increased risks of cardiovascular diseases (CVD). As temperatures increase globally, it is crucial to examine the potential increase in excess heat-related CVD (xHEAT-CVD) burden to inform strategies for adaptation ...
Wei-Lun Tsai   +8 more
doaj   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

Climatological Understanding of Heat and Cold Wave Variability in Eastern Uttar Pradesh

open access: yesJournal of Agrometeorology
This study examines the trends and impacts of heat waves (HWs) and cold waves (CWs) in Eastern Uttar Pradesh, India, from 1961 to 2020, utilizing gridded daily maximum and minimum temperature data from the Indian Meteorological Department.
RAJEEV BHATLA   +4 more
doaj   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

open access: yesArthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni   +7 more
wiley   +1 more source

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