Results 41 to 50 of about 34,458 (261)

Evidence for excess pore‐water pressure generated in subglacial sediment: Implications for clast ploughing

Geophysical Research Letters, 2005
Pore water pressure in front of an object pulled through subglacial sediment and water pressure at the base of a borehole were simultaneously recorded at Unteraargletscher, Switzerland, to investigate the generation of excess pore pressures downglacier from ploughing clasts.
Rousselot, Marie, Fischer, Urs H.
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Laboratory Tests on Open-Close Pile Jacking and Load Bearing Characteristics in Saturated Clay Soil

Advances in Civil Engineering, 2022
The stress characteristics of the pile-soil interface have an important influence on the effect and long-term bearing capacity of jacked piles. In order to obtain the stress characteristics of the pile-soil interface of the jacked pile in clay, the ...
Qiang Song, Teng Zhang, Guangyu Zhou, Hongzhong Li, Xianghou Li, Yishun Jiang, Peng Zhao, Weihui Tian, Yonghong Wang, Chuantong Zhang, Huining Liu   +10 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Large-scale shaking table tests on the liquefaction and deformation responses of an ultra-deep overburden

Open Geosciences
To study the liquefaction problem of the dam foundation of an ultra-deep overburden in the strong earthquake area, a large-scale shaking table model test is carried out based on a 500 m rockfill dam project on an ultra-deep overburden.
Xing Yang, Wentao Li, Shibin Wu, Zhixiong Chen, Xuanming Ding   +4 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Prediction of Excess Pore Water Pressure during Undrained Heating of Clays

, 2015
This paper focuses on the prediction of thermally-induced excess pore water pressure generation in saturated clays during undrained heating. This study involves an analysis of experimental data presented in the literature for normally consolidated clays with different mineralogical compositions.
Ghaaowd, Ismaail, Mccartney, John S
openaire   +3 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Determining the end of primary consolidation parameters based on settlement and excess pore water pressure [PDF]

Archives of Civil Engineering
The multiple-stage loading with reloading at EOP tests were carried out on two high-plasticity remoulded clays. One percentage of the initial value of an excess pore water pressure has been adopted as a reference for the end of the primary consolidation ...
Bartłomiej Szczepan Olek
doaj   +1 more source