Results 71 to 80 of about 170,516 (304)

The formation of nodular structures in the top layer of ultrafiltration membranes [PDF]

open access: yes, 1994
The formation of nodular structures in the top layer of ultrafiltration membranes is considered. A critical review of mechanisms described in the literature is given.
Smolders, C.A.   +4 more
core   +8 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Determining the end of primary consolidation parameters based on settlement and excess pore water pressure [PDF]

open access: yesArchives of Civil Engineering
The multiple-stage loading with reloading at EOP tests were carried out on two high-plasticity remoulded clays. One percentage of the initial value of an excess pore water pressure has been adopted as a reference for the end of the primary consolidation ...
Bartłomiej Szczepan Olek
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Understanding the microscopic moisture migration in pore space using DEM simulation

open access: yesJournal of Rock Mechanics and Geotechnical Engineering, 2015
The deformation of soil skeleton and migration of pore fluid are the major factors relevant to the triggering of and damages by liquefaction. The influence of pore fluid migration during earthquake has been demonstrated from recent model experiments and ...
Yuan Guo, Xiong (Bill) Yu
doaj   +1 more source

Stabilized material point methods for coupled large deformation and fluid flow in porous materials

open access: yes, 2019
The material point method (MPM) has been increasingly used for the simulation of large deformation processes in fluid-infiltrated porous materials. For undrained poromechanical problems, however, standard MPMs are numerically unstable because they use ...
Choo, Jinhyun, Zhao, Yidong
core   +2 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Study of the Pore Water Pressure Development Characteristics of PHC Pipe Piles in Soft Soil Foundations

open access: yesBuildings
When constructing hollow prestressed high-strength concrete (PHC) pipe piles in soft soil foundations, the generation and dissipation of pore water pressure can induce negative friction on the pile.
Zhaolin Jia   +4 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Field tests on excess pore pressure and soil pressure of pile-soil interface for a single pile during pile-sinking in clay

open access: yesYantu gongcheng xuebao, 2019
Stress change of pile-soil interface for jacked-in piles during pile-sinking in clay is a topic of concern in the geotechnical engineering. A full-scale jacked-in pile is penetrated into the clay in Dongying city of China and studied by monitoring the ...
WANG Yong-hong 1,2, ZHANG Ming-yi 1,2, LIU Jun-wei 1,2, BAI Xiao-yu 1,2, YANG Su-chun 1, SANG Song-kui 1, YAN Nan 3
doaj   +1 more source

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