Results 81 to 90 of about 170,516 (304)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

In-situ tests on pore-water pressure response and consolidation mechanism of surface sediments in tidal flat of Yellow River Delta under tide and wave loading

Yantu gongcheng xuebao
In order to study the pore pressure response and consolidation mechanism of the surface sediments in the tidal flat of the Yellow River Delta under the action of wave and tide loading, the fluid sediments imitating the rapidly deposited seabed silty ...
ZHANG Jianmin 1, 2, SHAN Hongxian 3, WANG Zhenqiang 1, 2, WANG Zhicai 1, 2, WANG Jinjin 1, 2
doaj   +1 more source

Field tests on response of excess pore water pressures of liquefaction resistant rigid-drainage pile

Yantu gongcheng xuebao, 2017
The liquefaction resistant rigid-drainage pile is a new type of pile which can be used in geotechnical earthquake engineering. The pile combines the bearing capacity of rigid pile and the drain-ability of gravel pile.
WANG Xiang-ying 1, 2, LIU Han-long 1, 2, 3, JIANG Qiang 1, 2, 4, CHEN Yu-min 1, 2
doaj   +1 more source

Stable hydrosols for TiO2 coatings [PDF]

, 2010
The optimum processing parameters required to synthesize, by hydrolysis of titanium isopropoxide (TIP), highly stable hydrosols composed of nanoparticles of the smallest possible size, are deduced both from data available in literature and from our own ...
Alphonse, Pierre, Tendero, Claire, Varghese, Aneesha Mary   +2 more
core   +2 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Stochastic Investigation of Consolidation Process in Spatially Correlated Heterogeneous Soils

Applied Sciences, 2017
Soil consolidation as the dissipation of excess pore water pressure is mainly affected by the relative hydraulic conductivity among the layers. Geostatistical parameters such as the mean, the standard deviation, and the correlation length are physical ...
Song-Hun Chong
doaj   +1 more source

Foundation stability on sandy soil due to excessive pore water pressure: laboratory observations

IOP Conference Series: Earth and Environmental Science, 2019
Abstract Pore water pressure is a factor which contributes to foundation stability. The change in pore water pressure in soil mass may affect the bearing capacity of the foundation. Especially for sandy soil, the increased pore pressure may cause the foundation collapse. This study investigates the stability of soil-foundation system due
A Hakam, R Yuliet, null Risayanti, H G Putra, null Sunaryo   +4 more
openaire   +1 more source

Preconditioning and triggering of offshore slope failures and turbidity currents revealed by most detailed monitoring yet at a fjord-head delta [PDF]

, 2016
Rivers and turbidity currents are the two most important sediment transport processes by volume on Earth. Various hypotheses have been proposed for triggering of turbidity currents offshore from river mouths, including direct plunging of river discharge,
Cartigny, Matthieu J.B., Clare, Michael A., Hughes Clarke, John E., Pratomo, D. G., Talling, Peter J.   +4 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source