Results 41 to 50 of about 3,148,287 (203)

Experimental Liquefaction Study of Southern Yogyakarta Using Shaking Table

open access: yesJurnal Teknik Sipil, 2017
An experimental study using shaking table was conducted to learn liquefaction. Samples used were sandy soils from South of Yogyakarta Special Region Province. Analysis of liquefaction potential was performed by considering several factors, i.e.
Lindung Zalbuin Mase
doaj   +1 more source

Dynamic responses of saturated soft soil foundation under high-speed train load

open access: yesRock and Soil Mechanics, 2021
Based on Biot's theory of porous media, this paper proposes a coupled vehicle-track-saturated foundation model to study the dynamic responses of saturated soft soil foundation under high-speed train load via two-and-half dimensional finite element ...
HU Jing   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Experimental Study on the Uplift Correction of Raft Foundations in Saturated Silty Clay

open access: yesBuildings
Although grouting technology has been widely applied for lifting and rectifying tilted structures, theoretical research remains underdeveloped and lags behind the practical demands of engineering applications. In this study, a self-developed experimental
Tengyue Cui, Yingguang Shi, Feng Huang
doaj   +1 more source

Compositional, mechanical and transport properties of carbonate fault rocks and the seismic cycle in limestone terrains: A case study of surface exposures on the Longmenshan Fault, Sichuan, China [PDF]

open access: yes, 2015
Destructive earthquakes are common in tectonically active regions dominated by carbonate cover rocks. The catastrophic Wenchuan earthquake that struck Sichuan, China, also affected a section of carbonate cover terrain.
Chen, Jianye   +2 more
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Field Test Investigation of the Pile Jacking Performance for Prefabricated Square Rigid-Drainage Piles in Saturated Silt Sandy Soils

open access: yesAdvances in Civil Engineering, 2019
The rigid-drainage pile, designed to accelerate the dissipation of excess pore water pressure around the pile, is a new type of pile that combines the bearing capacity of ordinary rigid piles and the draining capacity of gravel piles.
Xiangying Wang
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Experimental investigation on reinforcement and deformation control of soft clay using capsule expansion combined with electro-osmosis method

open access: yesYantu gongcheng xuebao
Grouting in soft clay for ground improvement generates significant excess pore water pressure and damages structure destruction, resulting in slight improvement of soil strength and appreciable settlement after grouting.
MENG Fanyan 1, 2, 3, TANG Yaofeng 1, 2, 3, ZHAO Rong 1, 2, 3, CHEN Tong 1, 2, 3, CHEN Renpeng 1, 2, 3
doaj   +1 more source

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