Results 21 to 30 of about 8,943,693 (261)

Macroeconomic Factors Driving Exchange Rate Volatility and Economic Sustainability: Case Study of Pakistan [PDF]

open access: yesAmfiteatru Economic
Volatility increases the risk of exchange rate, and the risk of exchange rate refers to losing money due to fluctuations in the exchange rate. Thus, it significantly impacts the country's economic development stability or sustainability, as making ...
Saghir Pervaiz Ghauri   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The private ECU’s potential impact on global and European exchange rate stability

open access: yesPSL Quarterly Review, 2013
This article examines the potential advantages and disadvantages of the creation of well-developed European Currency Unit (ECU) deposit and credit markets within the EEC. The major potential disadvantages are the higher speed of ECU creation and of intra-
H. JAGER, E . DE JONG
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Impact of exchange rate dynamics on economic growth

open access: yesВекторы благополучия: экономика и социум
This article explores the impact of exchange rate stability on economic growth in the context of increasing integration of national economies into global financial markets.
Nikita S. Malafeev   +2 more
doaj   +1 more source

L'impatto potenziale dell'ECU privato sulla stabilità di cambio globale ed europea. (The private ECU’s potential impact on global and European exchange rate stability)

open access: yesMoneta e Credito, 2013
Questo articolo esamina i potenziali vantaggi e svantaggi della creazione di mercati ben sviluppati European Currency Unit (ECU) di deposito e di credito nell'ambito della CEE.
H. JAGER, E. DE JONG
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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