Results 41 to 50 of about 3,290,268 (346)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Modern exchange rate formation in a resource-oriented economy: the institutional dimension
RUDN Journal of Economics, 2021 There is an increasing need for in-depth theoretical and applied studies of the essence, structure and features of the formation of the exchange rate, the development of the mechanism of currency regulation in the Russian Federation, determining the ...
Konstantin G. Bunevich +1 more
doaj +1 more source
Is a more stable exchange rate associated with reduced exchange rate pass-through? [PDF]
, 2007 Pass-through from the nominal effective exchange rate to import prices is modelled within a regime-switching environment. Evidence suggests that exchange rate pass through can be characterised as regime-specific where the probability of switching between
Holmes, Mark J.
core
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
The Interest Rate — Exchange Rate Nexus: Exchange Rate Regimes and Policy Equilibria [PDF]
We study a credible Markov-perfect monetary policy in an open New Keynesian economy with incomplete finacial markets. We demonstrate the existence of two discretionary equilibria. Following a shock the economy can be stabilised either 'quickly' or 'slow',
Christoph Himmels, Tatiana Kirsanova
core +3 more sources
Exchange-Rate Exposure of Multinationals: Focusing on Exchange- Rate Issues [PDF]
SSRN Electronic Journal, 2001 This paper examines exchange-rate exposure of multinationals (MNEs) in light of detailed exchange rate data. Specifically, using MNE-specific exchange rates and accounting for the possibility that exchange-rate crises may impact a firm differently than periods of normal fluctuations, estimates suggest ¼ of all MNEs had significant exchange rate ...
openaire +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
BANK OF RUSSIA’S EXCHANGE RATE POLICE AND OPTION OF EXCHANGE RATE REGIME
Мир новой экономики, 2018 The article devotes to such issues as the Russian current exchange rate police, the affected to exchange rate regime option factors, currency interventions, and aiming to smoothing extreme exchange rate volatility measures.
VALENTINA VIL’EVNA Kuznetsova
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The future exchange rate regime
PSL Quarterly Review, 2014 When the Committee of Twenty decided to rename the exchange-rate regime rather than reform it, some two weeks after the system had collapsed, it immediately became clear that the ambitious attempt to write a new monetary constitution for the world had ...
J. WILLIAMSON
doaj +1 more source