Results 61 to 70 of about 1,561,793 (312)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Exchange Rate Risk and the Macroeconomics of Exchange Rate Determination [PDF]
, 1980 This chapter addresses the question of what contribution finance theory can make to an explanation of exchange rate movements. It is an attempt to integrate ideas of finance theory such as portfolio diversification, efficiency, rationality,and use of information in a reasonably eclectic macroeconomic model and to study in that broadened context the ...
openaire +2 more sources
Asymmetric and Lag Effects of Industry Risk Factors on the Malaysian Oil and Gas Stocks
SAGE Open, 2023 This study examines asymmetric and the lag effects of oil price, gas price, and exchange rate on stock performance of the Malaysian oil and gas sub-industries.
Mohammad Enamul Hoque +4 more
doaj +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker +9 more
wiley +1 more source
The Foreign Exchange Risk Premium in a Target Zone with Devaluation Risk [PDF]
The foreign exchange risk premium in an exchange rate target zone regime with devaluation/realignment risks is derived. In contrast to previous literature, the exchange rate's heteroscedasticity within the bard, as well as a separate devaluation ...
Lars E.O. Svensson
core
Interest Rate and Foreign Exchange Risk Exposures of Australian Banks: A Note
The International Journal of Banking and Finance, 2009 The abolition of most government controls over the Australian financial system in the 1980s, the advent of a flexible exchange rate regime in 1983 and the globalisation of the financial system in the 1990s have created new opportunities for Australian ...
Abul F. M. Shamsuddin
doaj
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009 Investment opportunities into foreign curruncies financial assets are rising because of financial markets globalization, financial markets integration and evolution of modern information technologies.
Oldřich Šoba
doaj +1 more source
Research on RMB Exchange Rate Volatility Risk Based on MSGARCH-VaR Model
Discrete Dynamics in Nature and Society, 2020 This paper captures the RMB exchange rate volatility using the Markov-switching GARCH (MSGARCH) models and traditional single-regime GARCH models.
Xiaofei Wu, Shuzhen Zhu, Junjie Zhou
doaj +1 more source