Results 41 to 50 of about 11,803,794 (300)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Exchange Rate Risk and Interest Rate: A Case Study for Turkey [PDF]

open access: yesOpen Economies Review, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Berument H., Günay, A.
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

PENGARUH FAKTOR FUNDAMENTAL, FAKTOR RESIKO, DAN EKSPEKTASI NILAI TUKAR TERHADAP NILAI TUKAR RUPIAH (TERHADAP DOLLAR) PASCA PENERAPAN SISTEM KURS MENGAMBANG BEBAS PADA TANGGAL 14 AGUSTUS 1997 (PERIODE SEPTEMBER 1997 S.D. DESEMBER 2001)

open access: yesBuletin Ekonomi Moneter dan Perbankan, 2004
In a free floating rate system, the exchange rate is determined directly by market forces, and is liable to fluctuate continually, to follow changing market condition.
Indra Suhendra
doaj   +1 more source

Modelación de la Volatilidad del Tipo de Cambio del Dólar en el Perú: Aplicación de los Modelos GARCH y EGARCH

open access: yesRevista de Análisis Económico y Financiero, 2021
Policymakers need accurate forecasts about the future values ​​of exchange rates. This is due to the fact that exchange rate volatility is a useful measure of uncertainty about a country's economic environment.
Victor Chung Alva
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Determinants of real exchange rate movements in 15 emerging market economies

open access: yesBrazilian Journal of Political Economy, 2020
Previous work has established that an appreciation of the real effective exchange rate (REER) contributes to premature deindustrialization, less productive investment and dependence on commodity booms and busts in emerging markets economies (EME).
THOMAS GODA, JAN PRIEWE
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Empirical exchange rate models and currency risk: some evidence from density forecasts [PDF]

open access: yes, 2004
A large literature in exchange rate economics has investigated the forecasting performance of empirical exchange rate models using conventional point forecast accuracy criteria.
Sarno, Lucio, Valente, Giorgio
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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