Results 31 to 40 of about 9,400,773 (312)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Impact of exchange rate dynamics on economic growth
This article explores the impact of exchange rate stability on economic growth in the context of increasing integration of national economies into global financial markets.
Nikita S. Malafeev +2 more
doaj +1 more source
The contribution of the ECU to exchange-rate stability. A comment
The article is a brief note criticising some essential elements of Jager and De Jong’s The private ECU’s potential impact on Global and European exchange-rate stability (1988).
M. SARCINELLI
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Questo articolo esamina i potenziali vantaggi e svantaggi della creazione di mercati ben sviluppati European Currency Unit (ECU) di deposito e di credito nell'ambito della CEE.
H. JAGER, E. DE JONG
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
L'articolo è una breve nota critica alcuni elementi essenziali di Jager e De Jong del potenziale impatto del dell'ECU privato sulla stabilità dei tassi di cambio mondiale ed europeo ( 1988) .
M. SARCINELLI
doaj +1 more source
Money demand instability and real exchange rate persistence in the monetary model of USD-JPY exchange rate [PDF]
This article has been made available through the Brunel Open Access Publishing Fund.This paper proposes a hybrid monetary model of the dollar-yen exchange rate that takes into account factors affecting the conventional monetary model's building blocks ...
John Hunter (1349355) +3 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

