Results 31 to 40 of about 9,400,773 (312)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Impact of exchange rate dynamics on economic growth

open access: yesВекторы благополучия: экономика и социум
This article explores the impact of exchange rate stability on economic growth in the context of increasing integration of national economies into global financial markets.
Nikita S. Malafeev   +2 more
doaj   +1 more source

The contribution of the ECU to exchange-rate stability. A comment

open access: yesPSL Quarterly Review, 2013
The article is a brief note criticising some essential elements of Jager and De Jong’s The private ECU’s potential impact on Global and European exchange-rate stability (1988).
M. SARCINELLI
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

L'impatto potenziale dell'ECU privato sulla stabilità di cambio globale ed europea. (The private ECU’s potential impact on global and European exchange rate stability)

open access: yesMoneta e Credito, 2013
Questo articolo esamina i potenziali vantaggi e svantaggi della creazione di mercati ben sviluppati European Currency Unit (ECU) di deposito e di credito nell'ambito della CEE.
H. JAGER, E. DE JONG
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Il contributo dell'ECU alla stabilità dei cambi: una replica. (The contribution of the ECU to exchange-rate stability. A comment)

open access: yesMoneta e Credito, 2013
L'articolo è una breve nota critica alcuni elementi essenziali di Jager e De Jong del potenziale impatto del dell'ECU privato sulla stabilità dei tassi di cambio mondiale ed europeo ( 1988) .
M. SARCINELLI
doaj   +1 more source

Money demand instability and real exchange rate persistence in the monetary model of USD-JPY exchange rate [PDF]

open access: yes, 2014
This article has been made available through the Brunel Open Access Publishing Fund.This paper proposes a hybrid monetary model of the dollar-yen exchange rate that takes into account factors affecting the conventional monetary model's building blocks ...
John Hunter (1349355)   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy