Results 41 to 50 of about 31,637 (190)

Image_1_Efficacy of Whole-Blood Exchange Transfusion in Refractory Severe Autoimmune Haemolytic Anaemia Secondary to Systemic Lupus Erythematosus: A Real-World Observational Retrospective Study.jpg

, 2022
BackgroundSevere autoimmune haemolytic anaemia (AIHA) in systemic lupus erythematosus (SLE) patients could be life-threatening and formidable, especially in those nonresponsive to glucocorticoids (GCs) and immunosuppressants (ISAs).
Hong Jun Zhao (12855560), Bi Juan Li (12855563), Hui Luo (588276), Li Dan Zhao (12855569), Ying Jiang (5910), Xiao Xia Zuo (12855572), Zhi Min Zhang (12855566)   +6 more
core   +1 more source

Hemoglobin–albumin cluster: physiological responses after exchange transfusion into rats and blood circulation persistence in dogs

Artificial Cells Nanomedicine and Biotechnology, 2018
A core–shell protein cluster comprising hemoglobin and human serum albumins, hemoglobin–albumin cluster (Hb–HSA3), was designed and synthesized for use as an artificial O2 carrier and red blood cell (RBC) substitute.
H. Iwasaki, K. Yokomaku, Moeka Kureishi, Keisuke Igarashi, Ryo Hashimoto, M. Kohno, M. Iwazaki, Risa Haruki, Motofusa Akiyama, Ken-ichi Asai, Yuka Nakamura, Ryosuke Funaki, Y. Morita, T. Komatsu   +13 more
semanticscholar   +1 more source

Post-traumatic thrombotic microangiopathy following pelvic fracture treated with transcatheter arterial embolization: a case report

Journal of Medical Case Reports, 2018
Background Thrombotic microangiopathy is caused by various conditions, but few cases secondary to trauma have been reported. We present the rare case of a patient with thrombotic microangiopathy-induced high-impact trauma with hemorrhagic shock.
Kaori Ikegami, Takuma Yamagishi, Junya Tajima, Yukinori Inoue, Ken Kumagai, Yasuo Hirose, Daisuke Kondo, Koji Nikkuni   +7 more
doaj   +1 more source

Hemoglobin–albumin cluster: physiological responses after exchange transfusion into rats and blood circulation persistence in dogs

, 2019
A core–shell protein cluster comprising hemoglobin and human serum albumins, hemoglobin–albumin cluster (Hb–HSA3), was designed and synthesized for use as an artificial O2 carrier and red blood cell (RBC) substitute.
Ryosuke Funaki (6153839), Kenichi Asai (6153836), Teruyuki Komatsu (643617), Keisuke Igarashi (5557652), Risa Haruki (643615), Hitomi Iwasaki (6153833), Mitsutomo Kohno (190880), Kyoko Yokomaku (2136562), Moeka Kureishi (6040481), Motofusa Akiyama (1733584), Yoshitsugu Morita (1415701), Ryo Hashimoto (2196406), Yuka Nakamura (178929), Masayuki Iwazaki (4114669)   +13 more
core   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

Cholesterol exchange and synthesis in the live rat.

Journal of Lipid Research, 1985
The turnover of plasma cholesterol and de novo cholesterol synthesis were measured simultaneously in the live rat, immediately after administration of [3H]water together with a large volume exchange transfusion of whole blood prelabeled with [14C ...
S J Robins, J M Fasulo, M A Collins, G M Patton   +3 more
doaj   +1 more source

Large‐Scale Quantitative Morphometry of Platelet α‐Granules via SIM Super‐Resolution Microscopy for Cancer Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma, Huan Deng, Zelin Liu, Simei Zhong, Liangliang Wang, Mu He, Ning Jing, Lihua Dai, Yuzhen Basang, Xiao‐Yu Hu, Changyi Zhang, Huimin Zeng, Haoren Shao, Zhe Yang, Shanshan Zhao, Xiaohai Hu, Chuanjie Zhang, Xiaowei Wu, Jing Xu, Shaoqun Zeng, Jing Yuan, Qiang Li, Ziwei Qu, Zhenya Hong, Lingjuan Chen, Hanhua Dong, Jia Guo, Zhiqiang Han, Yu‐Hui Zhang   +28 more
wiley   +1 more source

Cerebral Blood Transit in Sickle Cell Anemia

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Sickle cell anemia (SCA) patients upregulate cerebral blood flow to compensate for decreased arterial oxygen content. Such hyperemic conditions can manifest as venous hyperintense signal on arterial spin labeling (ASL) MRI, which may reflect faster capillary blood transit, altered oxygen extraction fraction (OEF), and infarct risk ...
Wesley T. Richerson, Megan A. Aumann, Alexander K. Song, Samantha Davis, Lauren Milner, Maria Garza, Dann Martin, L. Taylor Davis, Sumit Pruthi, Lori C. Jordan, Manus J. Donahue   +10 more
wiley   +1 more source

Functional Repurposing of Magnetic Nanoparticle‐Assisted Hyperthermia for Immune Cell Labelling and Tracking

Small Methods, EarlyView.
We propose mild‐MHT protocol for the quick internalization of magnetic nanoparticles (MNPs) by immune cells. The heat induced by MNPs under alternating magnetic field stimulate MNPs diffusion and cell membrane invagination, accelerating the cellular internalization of MNPs. ABSTRACT Immune cell therapies show promise in hematologic malignancies and are
Giulia E. P. Nucci, Chiara Vitale, Alessandro di Girolamo, Niccolò Silvestri, Stefano Persano, Lorenci Gjurgjaj, Cristina Bottino, Roberta Castriconi, Teresa Pellegrino   +8 more
wiley   +1 more source

Parallel independent evolution of pathogenicity within the genus Yersinia. [PDF]

, 2014
The genus Yersinia has been used as a model system to study pathogen evolution. Using whole-genome sequencing of all Yersinia species, we delineate the gene complement of the whole genus and define patterns of virulence evolution.
Ringwood, T., Fookes, M, Riehm, JM, Hall, ME, Carniel, J, Harris, S. R., Fookes, M., Sihvonen, Leila M., Prentice, Michael B., Reuter, Sandra, Reuter, S, Sihvonen, LM, Fukushima, H., Corander, Jukka, Corander, J., Skurnik, M, Walker, Danielle, Harris, Simon R, Martin, L., Scholz, Holger C., Skurnik, Mikael, Shubin, M., Wren, BW, McNally, A, Skurnik, M., Ringwood, Tamara, Laukkanen-Ninios, R, Falcão, JP, Walker, D, McNally, Alan, Savin, Cyril, Barquist, L, Martin, Liliane, Barquist, L., Dufour, M, Fuchs, TM, Wren, Brendan W, Petty, Nicola K., Prentice, Michael B, Riehm, Julia M, Fuchs, Thilo M, McNally, A., Ringwood, T, Miettinen, M., Connor, T. R., Barquist, Lars, Hall, Miquette E, Laukkanen-Ninios, Riikka, Parkhill, Julian, Fukushima, Hiroshi, Bouchier, C., Bouchier, Christiane, Feltwell, Theresa, Prentice, M. B., Carniel, E, Thomson, NR, Siitonen, Anja, Achtman, M, Fuchs, T. M., Riehm, J. M., Martin, L, Petty, N. K., Shubin, M, Falcão, Juliana Pfrimer, Parkhill, J, Scholz, Holger C, Harris, Simon R., Hall, M. E., Dufour, M., Sihvonen, L. M., Scholz, HC, Feltwell, T, Bouchier, C, Miettinen, M, Thomson, N. R., Achtman, Mark, Corander, J, Prentice, MB, Harris, SR, Thomson, Nicholas R, Thomson, Nicholas R., Scholz, H. C., Carniel, Elisabeth, McNally, Alan; id_orcid, Fukushima, H, Wren, B. W., Fuchs, Thilo M., Petty, NK, Falcao, J. P., Connor, Thomas R, Savin, C, Riehm, Julia M., Parkhill, J., Wren, Brendan W., Sihvonen, Leila M, Savin, C., Laukkanen-Ninios, R., Feltwell, T., Petty, Nicola K, Carniel, E., Walker, D., Connor, Thomas R., Siitonen, A, Miettinen, Minna, Shubin, Mikhail, Reuter, S., Siitonen, A., Connor, TR, Fookes, Maria, Hall, Miquette E., Dufour, Muriel   +110 more
core   +1 more source