Results 51 to 60 of about 674,723 (265)

Exchange of values in contemporary religious architecture in poland symbol in the dialogue between east and west

open access: yesJournal of Architecture and Urbanism, 2009
Poland is situated in the area of cultural and religious borderland, in the sphere of Latin and Greek-Slavonic influence. The Author reviews the past and present examples of the exchange of values in the Christian Churches, i.e. the Eastern (Orthodox and
Jerzy Uścinowicz
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

An investigation on important factors influencing on forecasted earnings adjustment: Evidence from Tehran Stock Exchange [PDF]

open access: yesManagement Science Letters, 2014
This paper presents an empirical investigation to detect important factors influencing earning adjustment on firms selected on Tehran Stock Exchange over the period 2006-2011.
Fatemeh Babakhani   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The value of health information exchange

open access: yesJournal of Healthcare Leadership, 2012
Joshua E Richardson, Erika L Abramson, Rainu KaushalCenter for Healthcare Informatics and Policy, Weill Cornell Medical College, New York, NY, USAAbstract: Health information exchange (HIE) is a key component of health care reform that enables clinical ...
Richardson JE, Abramson EL, Kaushal R
doaj  

Literalizing Value: Poetry, Evaluation, and the Market in Marvell’s ‘The Last Instructions’

open access: yesMarvell Studies, 2018
Andrew Marvell’s poetic choices, especially his tendency to literalize metaphors, reveal a dissatisfaction with the growing prevalence of market exchanges in seventeenth-century England.
Ryan A Netzley
doaj   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The value of international scientific exchange

open access: yesCalifornia Agriculture, 1989
California Agriculture - All ...
K Farrel
doaj  

VALUE AT RISK ESTIMATION USING EXTREME VALUE THEORY APPROACH IN INDONESIA STOCK EXCHANGE

open access: yesBarekeng
Extreme Value Theory (EVT) is a method used to identify extreme cases in heavy tail data such as financial time series data. This research aimed to obtain an estimate of stock risk through the EVT approach and compare the accuracy of the two EVT ...
Fadhila Febriyanti Najamuddin   +2 more
doaj   +1 more source

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