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Drug Excipients

Current Medicinal Chemistry, 2006
The therapeutical use of drugs involves the application of dosage forms, serving as carrier systems together with several excipients to deliver the active ingredient to the site of action. Drug delivery technology combines an understanding of medicinal chemistry and pharmacology with the skill of formulation, aiming the preparation of improved ...
Huba, Kalász, István, Antal
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Pharmaceutical Excipients

Neonatal Network, 2000
WHY IS THE USE OF SINGLE-DOSE vials the norm in the NICU? Why is preservative-free parenteral solution standard care in the NICU? The simple response is that neonates are not just small adults. Children, especially neonates, differ from adults in their drug pharmacokinetics (absorption, distribution, metabolism, elimination).
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Fatal Excipients

American Journal of Forensic Medicine & Pathology, 2021
Abstract Crushed oral tablets, when injected intravenously, may induce a foreign body granulomatous reaction in and around pulmonary arterioles, because of the presence of filler materials (excipients). This typically presents as shortness of breath in the context of pulmonary hypertension with arteriolar dilation and centrilobular nodules on
Zarrin, Hossein-Zadeh   +2 more
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Excipients as stabilizers

Pharmaceutical Science & Technology Today, 1999
Excipients are better known as promoters of degradation than as stabilizers of drug substances. This is not surprising. Functional groups or residues in excipients can have the propensity to interact with labile active ingredients, with attendant loss of molecular integrity or other changes in quality.
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Excipients

2006
Lokesh Bhattacharyya   +3 more
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