Results 141 to 150 of about 453,414 (314)

EXCISION OF THE HUMERUS. [PDF]

The Lancet
n ...
openaire   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The Efficacy of Combination Therapy Involving Excision Followed by Intralesional 5-Fluorouracil and Betamethasone, and Radiotherapy in the Treatment of Keloids: A Randomized Controlled Trial

, 2022
Yazhuo Li, Dewu Zhang, Bing Hang, Hao Wang Department of Dermatology, the Second Affiliated Hospital of Xi’an Jiaotong University (Xibei Hospital), Xi’an, People’s Republic of ChinaCorrespondence: Hao Wang, Department of Dermatology, the Second ...
Li Y, Zhang D, Hang B, Wang H
core  

ON THE EXCISION OF TEETH. [PDF]

The Lancet
n ...
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Management of a Case of Lipoma Neck Excision with Difficult Airway using Superficial Cervical Plexus Block

, 2012
A mass in the neck could be associated with diifficult intubation, difficult mask ventilation, or both. We are reporting a case of lipoma of neck excision, with difficult airway, successfully managed by superficial cervical plexus nerve ...
Pradeep Hosagoudar, Sameena Kouser, Jaganath A, Rajesh Hiremath   +3 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

DNA polymerase B deficiency is linked to aggressive breast cancer: a comprehensive analysis of gene copy number, mRNA and protein expression in multiple cohorts

, 2014
Short arm of chromosome 8 is a hot spot for chromosomal breaks, losses and amplifications in breast cancer. Although such genetic changes may have phenotypic consequences, the identity of candidate gene(s) remains to be clearly defined.
Albarakati, N, Russell, R, Moseley, P, Moseley, Paul, Agarwal, D, Agarwal, Devika, Abdel-Fatah, TMA, Caldas, C, Abayomi, Michael Ayotunde, Chan, S, Ellis, IO, Russell, Roslin, Chan, Stephen, Madhusudan, Srinivasan, Abayomi, M, Ball, G, Perry, C, Madhusudan, S, Albarakati, Nada, Ball, Graham, Abdel-Fatah, Tarek M.A., Ellis, Ian O., Caldas, Carlos, Perry, Christina   +23 more
core   +1 more source

Improved Patient Outcomes with Electrocauterization Following Wedge Resection and Curettage for Ingrown Toenails: A Prospective Comparative Study

Archives of Plastic Surgery
Background Ingrown toenail is a common condition that results in chronic pain, recurrent infections, and difficulty in performing daily activities.
Marzouq Amarin, Raed Al-Taher, Khaled Daradka, Amal Ibraheem Abd al Qader Abu Harb, Rawan Abd AlMohsen Mohammad Habashneh, Nadwa Basem Bustami, Yazan Hijazein, Hiba Hadadin, Sondos Wa'el Sa'dat Al-Najjar   +8 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source