Results 191 to 200 of about 1,901,818 (345)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Feature-tuned excitation of somatostatin interneurons drives figure-ground segregation. [PDF]

Neuron
Zhang YE, Tao HW.
europepmc   +1 more source

Possibility of Excitation of Magnetospheric Modes by Strong Geomagnetic Storms

, 2017
Marcos Antônio Garcia, Andrés R. R. Papa   +1 more
openalex   +2 more sources

Non-reciprocity of magnon excitations in non-centrosymmetric magnets [PDF]

, 2018
雄介 井口
openalex   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Trion Transfer in Mixed-Dimensional Heterostructures. [PDF]

ACS Nano
Fang N, Erkiliç U, Chang YR, Fujii S, Yamashita D, Fong CF, Morito S, Kanahashi K, Taniguchi T, Watanabe K, Ueno K, Nagashio K, Kato YK.   +12 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Exploring Excited State Proton Transfer Dynamics upon Ultraviolet Excitation. [PDF]

J Phys Chem A
Kaul N, Benny A, Petropoulos V, Maj M, Cerullo G, Maiuri M, Scholes GD.   +6 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Dynamic response of Blue Honeysuckle fruit-stem system based on mathematical model. [PDF]

PLoS One
Wei Y, Ruiyin W, Yecheng W, Fang F, Decai M.   +4 more
europepmc   +1 more source