Results 171 to 180 of about 2,053,307 (308)
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Pérez Iruela, Manuel; Sáez Menéndez, Hilario; Trujillo Carmona, Manuel (coords.) (2002). Pobreza y exclusión social en Andalucía [PDF]
Luis Ayuso Sánchez
openalex +1 more source
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci+6 more
wiley +1 more source
La investigación sobre el desarrollo de la “Escuela Rural de Utawilaya y los Adventistas en el Altiplano puneño 1898 – 1920”, ubicada en la provincia de Puno del sur peruano, presenta como actor relevante al educador Manuel Zúñiga Camacho, fundador de ...
David Ruelas Vargas
doaj
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Role of medico-administrative database in the selection of the target population in colorectal cancer screening program. [PDF]
Koïvogui A+6 more
europepmc +1 more source
La educación para la dependencia, la exclusión y la pobreza en América Latina [PDF]
Germán Vargas Callejas
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Protective Factors Against Social Exclusion in Adolescents: Physical Condition and Physical Activity. [PDF]
Rodríguez-Negro J+4 more
europepmc +1 more source