Results 101 to 110 of about 20,644,730 (303)
Riesgo social de las personas en exclusión residencial: Un análisis multidimensional [PDF]
Having adequate housing is a basic requirement for social integration. However, residential exclusion is a permanent risk in our society for many groups and with very heterogeneous social profiles. The Observatory of Social Exclusion of the University of
Hernández-Pedreño, Manuel +2 more
core +1 more source
Política y Sociedad, 2009 El texto presenta una interpretación sociológica del fenómeno de la discapacidad que muestra cómo, a fecha actual en España, implica la posesión de una identidad social débil, heterónoma e impuesta por el entorno no-discapacitado así como unas ...
Miguel A.V. Ferreira +1 more
doaj
Social support modulates the neural correlates underlying social exclusion
Social Cognitive and Affective Neuroscience, 2019 Ostracism threatens the human need for social interactions, with negative consequences on cognition, affect and behavior. Understanding the mechanisms that can alleviate these consequences has therefore become an important research agenda. In this study,
R. Morese +4 more
semanticscholar +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Revista Española de Discapacidad, 2013 La discapacidad es una de las fuentes de discriminación más extendidas en la sociedad actual, reconocida con frecuencia por casi medio millón de personas en España, según cifras recientes.
Agustín Huete García
doaj
Social exclusion, marginalization and homelessness [PDF]
TemidaAlthough the concepts of marginalization and social exclusion are theoretically demarcated and defined, their connection becomes particularly visible when viewed through the prism of the phenomenon of homelessness. Social exclusion refers to the
Luković-Radaković Milica +1 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Personas con discapacidad: un desafío para Chile, Costa Rica, Ecuador y Uruguay
Perspectivas en InteligenciaLa discapacidad ha sido considerada históricamente un problema global que afecta a millones de personas, creando barreras que limitan la plena participación de estas en la sociedad.
María Eugenia Rodino-Bueno +3 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source