Results 121 to 130 of about 20,644,730 (303)
En las fronteras de la ciudadanía. Situación de las personas sin hogar y en riesgo de exclusión social en Madrid. [PDF]
, 2016 El libro se ha concebido como una herramienta que permita disponer de información contrastada de utilidad para el trabajo de gestores de políticas públicas, trabajadores y gestores de los recursos de atención social, académicos y cualquier otra personas
Vázquez Cabrera, José Juan +1 more
core
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Social exclusion (Wykluczenie Społeczne)
Contemporary Economics, 2011 Social exclusion (Wykluczenie Społeczne)
Janusz Czapiński, Tomasz Panek
doaj
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Exclusión y conocimiento social Exclusion and social knowledge
Sociologias, 2006 Raquel Sosa Elízaga
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
El sistema de protección social ante las situaciones de exclusión: exclusión social y desempleo [PDF]
, 2015 El empleo es el pilar central de la inclusión y su reverso, el desempleo, un elemento asociado a la pobreza y a la exclusión social. Por eso, cuando se trata de evaluar la eficacia del sistema de protección social ante las situaciones de vulnerabilidad y
Viqueira Pérez, Carmen
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source