Results 141 to 150 of about 20,644,730 (303)

Mental illness and social exclusion: assessment of the risk of violence after release. [PDF]

open access: yesRev Esp Sanid Penit, 2020
Fernández-García-Andrade R   +4 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Exclusión Social, Trabajo Comunitario y Resiliencia con Jóvenes

open access: yes, 2016
Las situaciones de vulnerabilidad social y en riesgo de exclusión que afectan a adolescentes y jóvenes más allá de la atención a necesidades puntuales, demandan un planteamiento global y de trabajo en red por parte de aquellas instituciones públicas y ...
Ruiz-Román, Cristóbal   +1 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Vivienda y desahucio, binomio inclusión-exclusión social [PDF]

open access: yes, 2017
La investigación que da pie a esta tesis doctoral, realiza una revisión de las medidas y mecanismos que la administración pública española, en el marco territorial autonómico, ha incorporado para hacer factible el acceso a una vivienda digna y adecuada ...
Arredondo Quijada, Rafael   +1 more
core  

Violencia, pobreza y exclusión social

open access: yesAlternativas, 2002
Linares Márquez de Prado, Esperanza
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Nuevos espacios del consumo y exclusión social.

open access: yesAnales de Geografía de la Universidad Complutense, 1998
Sin ...
Aurora García Ballesteros
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Vulnerabilidad y exclusión. Aportes para las políticas sociales [PDF]

open access: yes, 2017
grafs., tablasEsta publicación es el resultado de la convocatoria de la Red Temática de Políticas Sociales, Desarrollo y Protección Social de la Universidad de la República, a un conjunto amplio de personas, con diversas y acumulaciones, con el interés ...
Ministerio de Desarrollo Social (Uruguay)   +1 more
core  

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