Results 111 to 120 of about 4,057,435 (306)
About an alternative distribution function for fractional exclusion statistics
We show that it is possible to replace the actual implicit distribution function of the fractional exclusion statistics by an explicit one whose form does not change with the parameter $\alpha$.
Mehaute, A. Le +3 more
core +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Thermodynamic Properties of Generalized Exclusion Statistics
We analytically calculate some thermodynamic quantities of an ideal $g$-on gas obeying generalized exclusion statistics. We show that the specific heat of a $g$-on gas ($g \neq 0$) vanishes linearly in any dimension as $T \to 0$ when the particle number ...
Baez A V +10 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Football's Ability to Combat Social Exclusion [PDF]
Over the past few years there has been a clear shift in governmental focus on the role of sport within British society. The old maxim of ‘sport for sport’s sake’ has been largely superseded by an approach emphasising the role of sport in helping to ...
Long, J, Robinson, P
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The tension between planning and project-based urban planning is a classic debate in spatial planning. This tension is reinforced by the major transformations of Moroccan cities, particularly in their peripheries.
Maryame Amarouche
doaj +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
In South Africa, two principles apply to the exclusion of certain assets from an insolvent estate. First is the common-law principle that even the desperate insolvent is entitled to the basic necessities of life.
Zingapi Mabe, Edith Mbiriri
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

