Results 101 to 110 of about 2,663,449 (364)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Social Exclusion of the Elderly: A Comparative Study of EU Member States. ENEPRI Research Reports No. 57, 2 September 2008 [PDF]

open access: yes, 2008
Combating social exclusion is one of the key objectives of pension systems. This report focuses on social exclusion among the elderly (defined as the 55+ age group) in the EU’s member states.
Jehoel-Gijsbers, Gerda., Vrooman, Cok.
core  

Power of edge exclusion tests for graphical log-linear models

open access: yes, 2005
Asymptotic multivariate normal approximations to the joint distributions of edge exclusion test statistics for saturated graphical log-linear models, with all variables binary, are derived.
Salgueiro, Maria   +8 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Theories of social exclusion and the public library

open access: yes, 2000
“Social exclusion” has increasingly taken over from terms like poverty and deprivation as a term for describing social division. The paper considers social exclusion, and the related term “social inclusion”, and its implications for the public library ...
Muddiman, Dave
core  

Child social exclusion and health outcomes: a study of small areas across Australia [PDF]

open access: yes, 2014
Australian children living in areas with a relatively high risk of social exclusion also experience relatively poor health outcomes, argues this bulletin.

core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Finding Space in Politics: Perceptions of Representation Among Dutch Citizens With an Immigration Background

open access: yesPolitics and Governance
Representative democracy functions optimally when all citizens can participate, are heard, and feel represented. We know, however, that those interested and satisfied in politics rarely reflect a cross-section of the population.
Floris Vermeulen   +3 more
doaj   +1 more source

Niezapomniany rok 1942

open access: yesStudia Litteraria et Historica, 2014
The unforgotten 1942  Ewa Weinberg relates her story of the deportations of Polish citizens to the USSR in the summer of 1940 and their life in 1942. After the Sikorski-Majski Pact had been signed and Anders‘s Army established, the deportees tried to ...
Ewa Weinberg
doaj   +1 more source

Social exclusion mobility in Spain, 1994-2000 [PDF]

open access: yes
Social exclusion can be defined as a process leading to a state of multiple functioning deprivations. Cross-sectional headcount ratios of social exclusion may overstate the extent of the problem if most individuals do not remain in the same state in ...
Ambra Poggi
core  

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