Results 81 to 90 of about 2,425,360 (253)
Schools, Education and Social Exclusion [PDF]
A review of research evidence suggests that low levels of educational attainment are crucial in generating and sustaining social exclusion. Test scores at school are the most effective predictor of many adult outcomes.
Jo Sparkes
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The Wrongness of Preventive Exclusion
This chapter contends with the intuition that preventive exclusion is morally wrong. It considers two questions. First, what is a plausible basis for holding this intuition? Second, what is the extent of its wrongness?
Birks, David Rhys
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Social Exclusion and Children: A European view for a US debate [PDF]
The concept of social exclusion has been widely debated in Europe but its application to children has seen relatively little discussion. What could be meant by exclusion of children is the first main theme of the paper. Among other things, I consider the
John Micklewright
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Educational Inclusion: biopolitical approach related to the bicentennial
This paper studies the historical relationship between education and society based on a problematic element - inclusion. The commemoration of independence in American countries is addressed to show that different forms of educational inclusion seen today
Juan Carlos Echeverri-Alvarez
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Measuring Well-Being and Exclusion in Europes Regions [PDF]
The Lisbon summit of the European Council in March 2000 declared the number of people living in poverty and social exclusion in the European Union to be unacceptable, and called for steps to tackle the issue, beginning with the setting of targets for ...
Kitty Stewart
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Social Exclusion of the Elderly: A Comparative Study of EU Member States. ENEPRI Research Reports No. 57, 2 September 2008 [PDF]
Combating social exclusion is one of the key objectives of pension systems. This report focuses on social exclusion among the elderly (defined as the 55+ age group) in the EU’s member states.
Jehoel-Gijsbers, Gerda., Vrooman, Cok.
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