Results 141 to 150 of about 2,252,502 (296)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Expanding Horizons: Robotic Minimally Invasive Direct Coronary Artery Bypass with Left Atrial Appendage Exclusion - A Step Forward in Minimally Invasive Cardiac Surgery. [PDF]

Braz J Cardiovasc Surg
Saad A.
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

The impact of social exclusion on malevolent creativity in college students: the mediating role of aggression and the moderating effect of team sports participation-evidence from universities in Shanghai. [PDF]

Front Psychol
Shi J, Qiu H, Li J, Liu B.
europepmc   +1 more source

Scientific Rationale for the Inclusion and Exclusion Criteria for Intravenous Alteplase in Acute Ischemic Stroke: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

Stroke, 2016
B. Demaerschalk, D. Kleindorfer, O. Adeoye, A. Demchuk, J. Fugate, J. Grotta, Alexander A. Khalessi, E. Levy, Y. Palesch, S. Prabhakaran, G. Saposnik, J. Saver, Eric E. Smith   +12 more
semanticscholar   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Mammal defaunation leads to biotic homogenization of plant communities in tropical rainforests. [PDF]

Ecology
Ribas LGDS, Villar N, Zipparro V, Nazareth S, Souza Y, Brocardo CR, Schmaedecke G, Hortenci L, Alves RSC, Galetti M.   +9 more
europepmc   +1 more source

Transport and social exclusion: Where are we now?

, 2012
K. Lucas
semanticscholar   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

'They are lovely men': Compassionate exclusion used to justify a protest outside asylum seeker accommodation. [PDF]

Br J Soc Psychol
Nightingale A, Jay S.
europepmc   +1 more source