Results 141 to 150 of about 2,663,449 (364)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

HACKING THE CITY A SOMEWHAT DIFFERENT MODE OF FIELD WORK

open access: yesEuropean Journal of Geography, 2012
Guerilla Gardening, Reclaim the street, Adbusting and others are characteristic forms of temporary appropriation of public spaces. Those have become a global trend.
Romy HOFMANN, Martina MEHREN
doaj  

Representing social action in Indonesian: A case of Indonesian presidential race

open access: yesIndonesian Journal of Applied Linguistics, 2019
A large body of research on social action representation revolves around how social actors are discursively represented in a variety of media; nevertheless, very few discourse studies have investigated the Indonesian news media portrayal of an Indonesian
Agus Nero Sofyan, Mahardhika Zifana
doaj   +1 more source

The multi-dimensional analysis of social exclusion [PDF]

open access: yes, 2007
The purpose of this project was to review existing sources on multi-dimensional disadvantage or severe forms of social exclusion characterised as ‘deep exclusion’; to recommend possibilities for secondary analysis of existing data sets to explore the ...
Levitas, Ruth   +5 more
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Exclusion from School and Attention-Deficit / Hyperactivity Disorder. [PDF]

open access: yes, 2010
The exclusion of children from school, either on a fixed-term or a permanent basis, is a disciplinary tool used in primary and secondary schools throughout the United Kingdom.
O'Regan, Fintan, Fintan O’Regan
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

SPATIAL DIMENSION OF SOCIAL EXCLUSION. AN IMPERIAL INVESTIGATION INTO THE RELATIONSHIP OF HOUSING AND SOCIAL EXCLUSION IN THE SLUMS OF DHAKA CITY [PDF]

open access: yes
Slums are perceived to be heavily populated urban areas characterized by inadequate access to safe water, hygienic sanitation, urban roads, legitimate power supply, poor structural quality of housing and insecure residential status. From that perspective,
Halima BEGUM, Golam MOINUDDIN
core  

Exclusion-papers-SI-MDS-v1_online_supp – Supplemental material for Exclusion Criteria as Measurements I: Identifying Invalid Responses

open access: yes, 2019
Supplemental material, Exclusion-papers-SI-MDS-v1_online_supp for Exclusion Criteria as Measurements I: Identifying Invalid Responses by Barry Dewitt, Baruch Fischhoff, Alexander L. Davis, Stephen B. Broomell, Mark S.
Alexander L. Davis (7328771)   +5 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

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