Results 141 to 150 of about 789,134 (313)
Vertical integration and exclusive vertical restraints in health-care markets [PDF]
We examine vertical integration and exclusive vertical restraints in health-care markets where insurers and hospitals bilaterally bargain over contracts.
Rudy Douven +3 more
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Estimating complementarity among vertical restraints: Evidence from manufacturing firms [PDF]
This paper uses a bivariate probit model to analyze firms' decisions to impose regimes of exclusive dealing and/or exclusive territories with their distributors.
Daniel Miles, Xulia González
core
Exclusive photoproduction of ψ(2S) in electron-proton collision at hera / Zulidza Zulkaply [PDF]
, 2012 The exclusive photoproduction of y (2S)mesons, g
Zulidza, Zulkaply
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The inclusive-exclusive distinction in Tibeto-Burman languages
, 2010 A survey of 170 Tibeto-Burman languages showed 69 with a distinction between inclusive and exclusive first-person plural pronouns, 18 of which also show inclusive- exclusive in Idual.
LaPolla, Randy J.
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Data product pricing strategy: exclusive or non-exclusive pricing
大数据From the perspective of data trading practice, the pricing machanism for data trading is not mature.This study aims to explore the impact of "exclusive pricing" and "non-exclusive pricing" on all parties involved in transactions. By doing so, it not only
XU Yixuan, WU Bing
doaj +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source