Results 51 to 60 of about 3,910 (241)
Reasoning with Realistic Disjunctives
, 1984 The research reported here investigated how people interpret and reason with disjunctive statements. Experiment 1 demonstrated a general preference for exclusive over inclusive interpretations, although this varied as a function of the context in which ...
Stephen E. Newstead +2 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Crosslinguistic Consistency in the Interpretation of Logical Connectives: The case of English, Hungarian, Spanish, and Mandarin Chinese [PDF]
, 2023 Languages have constructions that convey the logical concepts of negation, conjunction, and disjunction. These constructions are often logically ambiguous.
Jasbi, Masoud +4 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
A Cultural Historical Activity Theoretical (CHAT) Framework for Understanding the Construction of Inclusive Education from Turkish Teachers' and Parents' Perspectives [PDF]
, 2016 : Inclusive education has become a global movement through the policies of the United Nations Educational, Scientific, and Cultural Organization (e.g., Salamanca Statement).
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Lexicalizing disjunction scope
, 2019 Tiwa (Tibeto-Burman; India) has two disjunctive particles, which give rise to different interpretations in sentences with other operators. I argue that this semantic distinction is not one of inclusive vs. exclusive disjunction, but one of scope.
Dawson, Virginia
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Towards an inclusive theory of participation in architecture and urbanism
, 2023 Recently, participation has become one of the most significant concepts widely deliberated in different scientific and humanitarian discussions. The notion of participation started to be analytically explored in various disciplines, encompassing other ...
MOHAMAD NASIM ALHANOUSHALKHALAF
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