Comprehensive profiling of somatic alterations and HRD characteristics in Chinese germline BRCA-mutated breast cancer patients. [PDF]
Cui H, Zhu M, Ling B, Zhang L.
europepmc +1 more source
Exact Discrete Stochastic Simulation With Deep‐Learning‐Scale Gradient Optimization
A 203,796‐parameter gene regulatory network classifies handwritten digits with 98.4% accuracy using exact stochastic dynamics. The framework decouples forward simulation from backward differentiation, making continuous‐time Markov chain models compatible with deep‐learning optimization.
Jose M. G. Vilar, Leonor Saiz
wiley +1 more source
The role of support on breastfeeding exclusivity and duration among African migrant mothers in the United States. [PDF]
Addy T +5 more
europepmc +1 more source
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker +11 more
wiley +1 more source
Estimating Costs of Market Exclusivity Extensions For 4 Top-Selling Prescription Drugs in the US.
Hong D +6 more
europepmc +1 more source
Strategic Drivers Behind Early Withdrawal of Orphan Designations in the EU: A Retrospective Analysis (2000-2024). [PDF]
Bouwman L, Castanheira M, Siotis G.
europepmc +1 more source
Mutational profiling in acute myeloid leukemia. [PDF]
DiNardo CD.
europepmc +1 more source
Genomic Characteristics of Bladder Cancer: An AACR Project GENIE Study. [PDF]
Braun JP +4 more
europepmc +1 more source
Interrogating Early Word Knowledge: Factors That Influence the Alignment Between Caregiver-Report and Experimental Measures. [PDF]
Weaver H, Saffran JR.
europepmc +1 more source
Identifying themes of protective behavioral strategies for marijuana use with structural topic modeling. [PDF]
Gray BA +6 more
europepmc +1 more source

