One Function One Tool? A Review on Mutual Exclusivity in Tool Use Learning in Human and Non-Human Species [PDF]
Frontiers in Psychology, 2021 The goal of this review is twofold: first to explore whether mutual exclusivity and functional fixedness overlap and what might be their respective specificities and second, to investigate whether mutual exclusivity as an inferential principle could be ...
Ildikó Király +2 more
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Fast Mutual Exclusivity Algorithm Nominates Potential Synthetic Lethal Gene Pairs Through Brute Force Matrix Product Computations [PDF]
Computational and Structural Biotechnology Journal, 2021 Mutual Exclusivity analysis of genomic aberrations contributes to the exploration of potential synthetic lethal (SL) relationships thus guiding the nomination of specific cancer cells vulnerabilities.
Paola Gasperini +2 more
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Modeling mutual exclusivity of cancer mutations. [PDF]
PLoS Computational Biology, 2014 In large collections of tumor samples, it has been observed that sets of genes that are commonly involved in the same cancer pathways tend not to occur mutated together in the same patient.
Ewa Szczurek, Niko Beerenwinkel
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A Network-Centric Framework for the Evaluation of Mutual Exclusivity Tests on Cancer Drivers [PDF]
Frontiers in Genetics, 2021 One of the key concepts employed in cancer driver gene identification is that of mutual exclusivity (ME); a driver mutation is less likely to occur in case of an earlier mutation that has common functionality in the same molecular pathway.
Cesim Erten, Rafsan Ahmed, Hilal Kazan
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gcMECM: graph clustering of mutual exclusivity of cancer mutations [PDF]
BMC Bioinformatics, 2021 Background Next-generation sequencing platforms allow us to sequence millions of small fragments of DNA simultaneously, revolutionizing cancer research.
Ying Hu +3 more
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Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer [PDF]
npj Breast Cancer, 2022 Both TP53 and ESR1 mutations occur frequently in estrogen receptor positive (ER+) metastatic breast cancers (MBC) and their distinct roles in breast cancer tumorigenesis and progression are well appreciated.
Zheqi Li +7 more
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The role of speaker accuracy and mutual exclusivity in children’s novel word learning [PDF]
PLoS ONEChildren draw on multiple sources of information during word learning, including speaker testimony and lexical expectations. Yet, little is known about how these cues jointly influence children's ability to learn new words. The present study examined the
Shalini Banerjee, Ishanti Gangopadhyay
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Meta-analysis reveals Helicobacter pylori mutual exclusivity and reproducible gastric microbiome alterations during gastric carcinoma progression [PDF]
Gut Microbes, 2023 Accumulating evidence shows that the gastric bacterial community may contribute to the development of gastric cancer (GC). However, the reported alterations of gastric microbiota were not always consistent among the literature.
Yan Li +7 more
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Where’s the Advantage? Mutual Exclusivity Promotes Children’s Initial Mapping, but Not Long-Term Memory, for Words Compared to Other Strategies [PDF]
Frontiers in Psychology, 2021 Children frequently apply a novel label to a novel object, a behavior known as the mutual exclusivity bias (MEB). This study examined how MEB affects children’s retention for word mappings.
Catherine A. Bredemann, Haley A. Vlach
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A pathway-informed mutual exclusivity framework to detect genetic interactions in pediatric cancer [PDF]
BMC Medical GenomicsBackground The exponential increase of sequenced cancer genomes has enabled the in-silico study of genetic interactions in tumors across many cancer types—particularly synthetic lethality, where two gene alterations lead to cell death—and identify new ...
Anastasia Spinou +3 more
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