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2019
The process of urine formation and xenobiotic excretion begins with the passage of blood through the glomerulus to yield a tubular fluid which is essentially an ultrafiltrate of plasma. Excretion of methotrexate, an organic anion, is inhibited by salicylates which compete for tubular transport.
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The process of urine formation and xenobiotic excretion begins with the passage of blood through the glomerulus to yield a tubular fluid which is essentially an ultrafiltrate of plasma. Excretion of methotrexate, an organic anion, is inhibited by salicylates which compete for tubular transport.
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1975
Certain chemical substances are produced in excessive quantities in animal tissues as a consequence of life processes, and must be eliminated from active metabolic sites before they cause problems for the organisms involved. The concentration at which these substances may become obtrusive varies widely depending upon the chemical nature and state of ...
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Certain chemical substances are produced in excessive quantities in animal tissues as a consequence of life processes, and must be eliminated from active metabolic sites before they cause problems for the organisms involved. The concentration at which these substances may become obtrusive varies widely depending upon the chemical nature and state of ...
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Medical Journal of Australia, 1967