Results 51 to 60 of about 2,868,111 (311)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
ON ROLE AND CONTRIBUTION OF THE CONSEIL D’ETAT IN LEGISLATION
During the 20th century, throughout the Western world, a process of democratisation (legislative) of delegation occurred in a way which is consistent with the specifi c historical experience and constitutional traditions of each country in particular ...
Petar Bačić
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The rule of law sets as an important principle entrenched in the Constitution of Malaysia and Indonesia. This principle stand as a guardian against abuse of power by the government as nobody shall be above the law.
Norazlina binti Abdul Aziz +1 more
doaj
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Two of the most discussed administrative-law theories in contemporary discussion are executive preemption and big waiver. Executive preemption is the idea that agency regulations preempt state law by extension of the federal statutes the agencies are ...
Russell, David
core +2 more sources
Is executive impairment associated with schizophrenic syndromes? A meta-analysis [PDF]
Original article can be found at: http://journals.cambridge.org/ Copyright Cambridge University Press. DOI: 10.1017/S0033291708003887A key neuropsychological proposal in schizophrenia is that negative and disorganization symptoms are associated with ...
Dibben, C.R.M. +3 more
core +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The impact of sleep quality on cognitive functioning in Parkinson's disease [PDF]
In healthy individuals and those with insomnia, poor sleep quality is associated with decrements in performance on tests of cognition, especially executive function. Sleep disturbances and cognitive deficits are both prevalent in Parkinson's disease (PD).
Bogdanova, Y. +4 more
core +6 more sources

