Results 71 to 80 of about 1,819,207 (290)

Dysexecutive difficulty and subtle everyday functional disabilities: the digital Trail Making Test

Frontiers in Neurology
BackgroundDigital neuropsychological tests reliably capture real-time, process-based behavior that traditional paper/pencil tests cannot detect, enabling earlier detection of neurodegenerative illness. We assessed relations between informant-based subtle
David J. Libon, David J. Libon, Rod Swenson, Sean Tobyne, Ali Jannati, Ali Jannati, Daniel Schulman, Catherine C. Price, Melissa Lamar, Alvaro Pascual-Leone, Alvaro Pascual-Leone, Alvaro Pascual-Leone   +11 more
doaj   +1 more source

An effect of inhibitory load in children while keeping working memory load constant

Frontiers in Psychology, 2014
People are slower and more error-prone when the correct response is away from a stimulus (incongruent) than when it is towards a stimulus (congruent). Two reasons for this are possible.
Adele eDiamond, Andy eWright, Andy eWright   +2 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Attentional Functioning in Healthy Older Adults and aMCI Patients: Results from the Attention Network Test with a Focus on Sex Differences

Brain Sciences
Background/Objectives: The prognostic uncertainty of Mild Cognitive Impairment (MCI) imposes comprehensive neuropsychological evaluations beyond mere memory assessment.
Laura Facci, Laura Sandrini, Gabriella Bottini   +2 more
doaj   +1 more source

Lifespan development of attentiveness in domestic dogs: drawing parallels with humans

Frontiers in Psychology, 2014
Attention is pivotal to consciousness, perception, cognition, and working memory in all mammals, and therefore changes in attention over the lifespan are likely to influence development and aging of all of these functions.
Lisa Jessica Wallis, Friederike eRange, Corsin A. Müller, Samuel eSerisier, Ludwig eHuber, Zsófia eVirányi   +5 more
doaj   +1 more source

Dopamine and the development of executive dysfunction in autism spectrum disorders. [PDF]

, 2015
Persons with autism regularly exhibit executive dysfunction (ED), including problems with deliberate goal-directed behavior, planning, and flexible responding in changing environments.
Kriete, Trenton, Noelle, David C
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Investigating the role of executive attentional control to self-harm in a non-clinical cohort with borderline personality features.

Frontiers in Behavioral Neuroscience, 2014
Self-injurious behavior (or self-harm) is a frequently reported maladaptive behavior in the general population and a key feature of borderline personality disorder (BPD).
Jennifer eDrabble, David P Bowles, Lynne Ann Barker   +2 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Development and evaluation of a Fault-Tolerant Multiprocessor (FTMP) computer. Volume 2: FTMP software [PDF]

The software developed for the Fault-Tolerant Multiprocessor (FTMP) is described. The FTMP executive is a timer-interrupt driven dispatcher that schedules iterative tasks which run at 3.125, 12.5, and 25 Hz.
Lala, J. H., Smith, T. B., III
core   +1 more source