Results 51 to 60 of about 268,081 (265)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The Effect of Confidence Rating on a Primary Visual Task

open access: yesFrontiers in Psychology, 2019
The current study explored the influence of confidence rating on visual acuity. We used brief exposures of the Landolt gap discrimination task, probing the primary visual ability to detect contrast.
Taly Bonder, Daniel Gopher
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Working Memory Deficits After Lesions Involving the Supplementary Motor Area

open access: yesFrontiers in Psychology, 2018
The Supplementary Motor Area (SMA)—located in the superior and medial aspects of the superior frontal gyrus—is a preferential site of certain brain tumors and arteriovenous malformations, which often provoke the so-called SMA syndrome.
Alba Cañas   +7 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Executive Control of Attention in Narcolepsy

open access: yesPLoS ONE, 2012
Narcolepsy with cataplexy (NC) is a disabling sleep disorder characterized by early loss of hypocretin neurons that project to areas involved in the attention network. We characterized the executive control of attention in drug-free patients with NC to determine whether the executive deficits observed in patients with NC are specific to the disease ...
Sophie Bayard   +4 more
openaire   +4 more sources

Negative Emotional Stimuli Enhance Conflict Resolution Without Altering Arousal

open access: yesFrontiers in Human Neuroscience, 2019
In our daily life, we frequently need to make decisions between competing behavioral options while we are exposed to various contextual factors containing emotional/social information.
Daniel J. Fehring   +6 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The role of economic evaluation in public health emergency management of disease outbreaks in Africa: a qualitative research

open access: yesHealth Economics Review
Background Recurrent disease outbreaks impose severe health and economic burdens on Africa, exposing critical gaps in public health emergency management (PHEM).
Elias Asfaw Zegeye   +2 more
doaj   +1 more source

Can task-switching training enhance executive control functioning in children with attention deficit/-hyperactivity disorder?

open access: yesFrontiers in Human Neuroscience, 2012
The key cognitive impairments of children with attention deficit/-hyperactivity disorder (ADHD) include executive control functions such as inhibitory control, task switching, and working memory.
Jutta eKray   +3 more
doaj   +1 more source

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