Results 91 to 100 of about 267,358 (306)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The roles of language and executive function in Mandarin-speaking children’s theory of mind development

Frontiers in Psychology
IntroductionResearch has indicated that language and executive function relate closely to first-order false belief reasoning, yet their roles in second-order false belief reasoning are under-explored, and their interplay in theory of mind development ...
Honglan Li, Man-Tak Leung
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Domain-specific skills, but not fine-motor or executive function, predict later arithmetic and reading in children

, 2022
Fine motor skills and executive function are two examples of domain-general skills. Both are correlates of arithmetic and reading ability, and have been identified as predictors of school readiness.
Hulme, Charles, Pritchard, Verena E, Malone, Stephanie A   +2 more
core   +1 more source

Rehabilitasi Neuropsikologi Dalam Upaya Memperbaiki Defisit Executive Function (Fungsi Eksekutif) Klien Gangguan Mental

Journal An-Nafs: Kajian Penelitian Psikologi, 2016
Executive function is responsible for directing self behavior in order to purposive and aims such as planning, organizing, problem solving, self-monitoring skills and self regulation. This function is associated with frontal lobe (center of think).
Nur Fatwikiningsih
doaj   +3 more sources

Physical activity and executive function in Chinese preschool children: the mediating role of sleep problems

Frontiers in Psychology
ObjectiveThis study aimed to examine the relationship between physical activity and executive function in preschool children, with a particular focus on the mediating role of sleep problem.MethodsA total of 159 preschool children participated in this ...
Xiaolong Chen, TianChang Li, TianChang Li, Weiling Zhou, Lancheng Huang, Sanhua Zhang, Sanhua Zhang   +6 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Inside or outside? The role of classroom setting location on child executive function

Acta Psychologica
Spending time in nature can have many benefits, particularly for executive function. This explorative study examined the difference between learning settings on child's executive function in Australian children aged 8 to 10 (N = 24, female = 50%).
Michael J.A. Down, Vanessa Charlton, Brock Freeman, Emilie Skoglys, Tonia Gray, Shyam Drury, Rebecca Mola, Duncan Picknoll, Fiona Farringdon   +8 more
doaj   +1 more source