Results 121 to 130 of about 1,080,536 (302)

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Neuropsychological assessment of executive functions: methodological questions / Avaliação neuropsicológica das funções executivas: considerações metodológicas

Psicologia: Reflexão e Crítica, 2009
The article aims to review methodological and conceptual issues related to neuropsychological assessment of executive functions. The main limitations and dichotomies of current studies related to executive functions are presented and the importance of ...
Amer Cavalheiro Hamdan, Ana Paula de Almeida Pereira   +1 more
doaj  

The most frequently used tests for assessing executive functions in aging

Dementia & Neuropsychologia
There are numerous neuropsychological tests for assessing executive functions in aging, which vary according to the different domains assessed. OBJECTIVE: To present a systematic review of the most frequently used instruments for assessing executive ...
Camila de Assis Faria, Heloisa Veiga Dias Alves, Helenice Charchat-Fichman   +2 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

The Comparison of the Executive-Neurological Functions of the Narcotic Addicted and Normal Adults

Research on Addiction, 2010
Aim: The purpose of present research was the comparison of executive-neurological functions of narcotics addicted and normal adults. Method: In this causal-comparative study 38 narcotics addicted person selected of two addiction treatment clinics in ...
Fereshteh Amini, Hamid Alizadeh, Omid Rezaee   +2 more
doaj  

Executive Functions and Special Educational Needs and Their Relationship with School-Age Learning Difficulties

Children
Background/Objectives: The relationship between executive functions, special educational needs (SEN), and learning difficulties in school-aged children is critical for developing effective educational interventions.
Juan Manuel Núñez, Ana Soto-Rubio, Marián Pérez-Marín   +2 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Comparing Executive Functions in Bilinguals and Monolinguals Suffering From Relapsing-Remitting Multiple Sclerosi

Journal of Modern Rehabilitation, 2019
Introduction: Executive functions generally refer to cognitive functions involved in the control and regulation of goal-directed behavior also the formation of mental representations.
Majid Soltani, Seyedeh Fatemeh Emami Dehcheshmeh, Negin Moradi, Alireza Hajiyakhchali, Nastaran Majdinasab, Seyed Mahmood Latifi, Masoume Hosseini beidokhti   +6 more
doaj