Results 51 to 60 of about 1,541,162 (315)
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Interpreting Presidential Powers [PDF]
, 2013 Justice Holmes famously observed that [g]reat cases . . . make bad law. The problem may be especially acute in the domain of national security, where presidents frequently interpret their own powers without judicial review and where executive ...
Fallon, Richard H., Jr.
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Brésil(s), 2014 This article shows that anti-legislative arguments in Brazil were reinforced in the 1970s by a new literature that presented itself as the vehicle for a new academic perspective that was not only innovative but also rigorous in its research.
Maria Celina D’Araujo
doaj +1 more source
Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim +3 more
wiley +1 more source
Проблеми Законності, 2019 The article analyzes the supreme bodies of state power under the Constitution of Pylyp Orlyk of 1710 and the Constitution of Poland of 1791 concerning the application of the principle of separation of state power into legislative, executive and judicial ...
Анатолій Іванович Козаченко
doaj +1 more source
Liberalism and Policing: The State We're In [PDF]
, 2018 Short online essay on the state of policing in liberal societies, discussing how executive discretionary power has grown to such a degree that it has trended toward illiberal practices and ...
Hunt, Luke William
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Судебный порядок обжалования подзаконных нормативно-правовых актов органов исполнительной власти
Теорія і практика правознавства, 2019 В статье исследованы проблемные вопросы обжалования подзаконных нормативно-правовых актов органов исполнительной власти Украины. Установлено, что порядок обжалования нормативно-правовых актов органов исполнительной власти можно разделить на ...
Євген Анатолійович Гетьман +1 more
doaj +1 more source
, 2013 This essay reviews Power and Constraint: The Accountable Presidency After 9/11 by Jack Goldsmith (2012). With The Terror Presidency, Professor Jack Goldsmith wrote, hands down, the very best analysis of the national security issues surrounding President ...
Katyal, Neal K.
core +1 more source