Results 111 to 120 of about 1,136,050 (252)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

EXERCISE ADDICTION – GENDER DIFFERENCES [PDF]

, 2013
Mnoga su istraživanja potvrdila dobrobit vježbanja i sporta za tjelesno i mentalno zdravlje. Posljednjih godina sve se više istražuju i negativni učinci tjelesnog vježbanja koji se vežu uz fenomen ovisnosti o vježbanju. Cilj ovog rada bio je ispitati
Vižintin, Marko, Barić, Renata
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

The relationship between physical exercise and academic burnout in adolescents: the chain-mediated role of internet addiction and self-control

Frontiers in Psychology
BackgroundAcademic burnout represents a pressing issue among adolescents in China and has garnered increasing attention from scholars in the sport science domain.
Jianbin Du, Jiahui Dong, Yan Shi, Enmeng Jiang, Lin Mo, Bingzhi Wan, Bingzhi Wan   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Sex Addiction: the Chicken-and-Egg Dilemma of Diagnosis [PDF]

, 2013
In May 2013, the American Psychiatric Association will release the next version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V). Interestingly, sex addiction, despite significant attention from mainstream media, will be omitted from ...
Berry, MD
core  

THE RELATIONSHIP BETWEEN EXERCISE ADDICTION AND PERCEIVED SERVICE QUALITY IN FITNESS CENTERS

Spormetre Beden Eğitimi ve Spor Bilimleri Dergisi
: This study aims to examine the relationship between exercise addiction levels and perceived service quality among fitness center members. Employing a relational survey model, data were collected via questionnaires from 244 voluntary participants who ...
Fatih Mehmet Parlar
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Physical exercise and bedtime procrastination among college students: mediating roles of self-control and mobile phone addiction

Frontiers in Psychology
BackgroundSleep is a crucial foundation for maintaining both physical and mental health. Bedtime procrastination has been identified as a significant behavioral factor contributing to decreased sleep quality.
Yangping Wang, Yangping Wang, Yangping Wang, Xudong Wang, Xudong Wang, Shanshan Wu, Shanshan Wu, Weijie Zhang, Weijie Zhang, Jingjing Li, Jingjing Li, Bing Liu, Bing Liu   +12 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source