Results 111 to 120 of about 173,407 (292)
Comorbidities and Race/Ethnicity Among Adults with Stimulant Use Disorders in Residential Treatment [PDF]
Comorbid physical and mental health problems are associated with poorer substance abuse treatment outcomes; however, little is known about these conditions among stimulant abusers at treatment entry.
Carmody, Thomas +5 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
THE RELATIONSHIP BETWEEN EXERCISE ADDICTION AND PERCEIVED SERVICE QUALITY IN FITNESS CENTERS
: This study aims to examine the relationship between exercise addiction levels and perceived service quality among fitness center members. Employing a relational survey model, data were collected via questionnaires from 244 voluntary participants who ...
Fatih Mehmet Parlar
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
BackgroundSleep is a crucial foundation for maintaining both physical and mental health. Bedtime procrastination has been identified as a significant behavioral factor contributing to decreased sleep quality.
Yangping Wang +12 more
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Wenxia Tong, Shuqiao Meng College of Physical Education, Yangzhou University, Yangzhou, People’s Republic of ChinaCorrespondence: Wenxia Tong, College of Physical Education, Yangzhou University, Yangzhou, 225000, People’s Republic of China, Tel +86 ...
Tong W, Meng S
doaj
Metabolic changes to GLUT-4 levels in urban Chacma baboons on the Cape Peninsula: raiding their way to type 2 diabetes? [PDF]
The Chacma baboons (Papio ursinus) of the Cape Peninsula are established raiders of human food, leading to widespread conflict between this intelligent, adaptable species and humans.
Van Velden, Julia
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

