Results 131 to 140 of about 173,407 (292)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effects of physical exercise on mindfulness level among female college students: the mediating effect of mobile phone addiction

Frontiers in Psychology
BackgroundThis study explores the impact of physical exercise on female college students’ trait mindfulness levels and examines the mediating role of mobile phone addiction in this relationship.MethodsThe empirical study employs stratified random cluster
JiaYi Li, YiKun Zheng, LiHan Lin, LiHan Lin, XiuQi Li, GuoPeng Hu   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Scoping review of therapeutic approaches among individuals with secondary exercise addiction

Frontiers in Psychiatry
Secondary exercise addiction shows high comorbidity with eating and body image disorders. Despite its substantial impact on physical and mental health and daily functioning, evidence on effective therapeutic interventions remains limited. The aim of this
Magdalena Jaroch-Lidzbarska, Magdalena Jaroch-Lidzbarska, David Alarcón, Henryk Olszewski, Dominika Wilczyńska   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Influence of smartphone addiction on sleep quality of college students: The regulatory effect of physical exercise behavior.

PLoS ONE
Due to the high incidence of smartphone addiction and its harmful effects on health in recent years, it has received widespread attention from society.
Weidong Zhu, Jun Liu, Hu Lou, Fanzheng Mu, Bo Li   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Changing my life one step at a time – using the Twelve Step program as design inspiration for long term lifestyle change [PDF]

, 2012
To explore how people manage and maintain life style change, we conducted interviews with eight members of different Twelve Step Fellowships with 2-23 years of recovery about how they maintain and develop their recovery in everyday life.
Nylander, Stina
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

EVALUATION OF BODY COMPOSITION, NUTRITIONAL STATUS, AND EATING ATTITUDES OF MALE INDIVIDUALS BASED ON EXERCISE ADDICTION BEHAVIOR

Spormetre Beden Eğitimi ve Spor Bilimleri Dergisi
In this study, we aimed to examine the body composition, supplement use and nutritional status of young adult males who attend the gym based on their level of exercise addiction.
Gizem Helvacı, Serap Balaban, Asli Uçar   +2 more
doaj   +1 more source