Results 111 to 120 of about 1,276,748 (319)

Combined Use of Stress Echocardiography and Cardiopulmonary Exercise Testing to Assess Exercise Intolerance after Acute Myocardial Infarction [PDF]

, 2020
Krzysztof Smarż, Tomasz Jaxa-Chamiec, Beata Zaborska, Maciej Tysarowski, Andrzej Budaj   +4 more
openalex   +1 more source

WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome [PDF]

, 2023
Pingyuan Wang, Jin Ma, Young‐Chae Kim, Annie Y. Son, Abu Mohammad Syed, Chengyu Liu, Mateus Prates Mori, Rebecca D. Huffstutler, JoEllyn Stolinski, S. Lalith Talagala, Ju‐Gyeong Kang, Brian Walitt, Avindra Nath, Paul M. Hwang   +13 more
openalex   +1 more source

Treatment recommendations for psoriatic arthritis [PDF]

, 2008
Objective: To develop comprehensive recommendations for the treatment of the various clinical manifestations of psoriatic arthritis (PsA) based on evidence obtained from a systematic review of the literature and from consensus opinion.
Boehncke, Wolf-Henning, Fiorentino, David, FitzGerald, Oliver, Gladman, Dafna D., Gottlieb, Alice B., Helliwell, Philip, Kavanaugh, Arthur, McHugh, Neil J., Mease, Philip J., Nash, Peter, Qureshi, Abrar A., Ritchlin, Christopher T., Soriano, Enrique R., Taylor, William J., Vlam, Kurt de   +14 more
core   +3 more sources

A Twist in the Diagnosis: Chronic Arthropathy Without Inflammation

Arthritis Care &Research, EarlyView.
María Á. Puche‐Larrubia, Inmaculada C. Aranda‐Valera, Alejandro Escudero‐Contreras, Rosa Roldán‐Molina   +3 more
wiley   +1 more source

Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities

Advanced Science, EarlyView.
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao, Lifeng Liang, Ling Yang, Chunyu Lyu, Yang Lyu, Weijun Yang, Jiaran Shi, Wei Wei, Jiahui Cheng, Xiaolei Sun, Xian Zhu, Chao Chen, Xiaoting Xu, Jianchuang Qi, Wenli Li, Yizhe Zhang, Xiao Zhang, Yan Zhou, Aiqiang Dong, Juntao Chen, Bo Li, Kun Yang   +21 more
wiley   +1 more source

Association of exercise-induced pulmonary hypertension with nailfold capillary density in systemic sclerosis: a single-center retrospective observational study

Arthritis Research & Therapy
Objectives Exercise-induced pulmonary hypertension (exercise PH) is instrumental in the early detection of pulmonary arterial hypertension. However, the prevalence and specific characteristics of exercise PH in systemic sclerosis (SSc), as well as ...
Katsuhide Kusaka, Satoshi Kubo, Shingo Nakayamada, Ippei Miyagawa, Yusuke Miyazaki, Yurie Kanda, Yasuyuki Todoroki, Masanobu Ueno, Ryuichiro Kanda, Koshi Setoyama, Masaharu Kataoka, Yoshiya Tanaka   +11 more
doaj   +1 more source

Clinical utility of exercise training in heart failure with reduced and preserved ejection fraction [PDF]

, 2015
Reduced exercise tolerance is an independent predictor of hospital readmission and mortality in patients with heart failure (HF). Exercise training for HF patients is well established as an adjunct therapy, and there is sufficient evidence to support the
Goh, CY, Hare, David L, Levinger, Itamar, Ul Haq, MA, Wong, C   +4 more
core   +2 more sources

Trigonelline Improves Metabolism and Cardiac Function of HFpEF Mice Via Gut Microbiome Alterations‐Mediated AMPK Activation

Advanced Science, EarlyView.
Metabolomics analyses reveal that trigonelline is markedly reduced in HFpEF hearts. Trigonelline supplementation alleviates metabolic disorders and improves cardiac function in HFpEF mice via gut microbiota‐mediated AMPK activation. Abstract Heart failure with preserved ejection fraction (HFpEF) is a prevalent end‐manifestation of cardiovascular ...
Zhe Cheng, Xiaowen Wang, Jiang Yu, Xiaorong Li, Qing Tang, Can Qu, Ding Yang, Yuanjing Li, Yong Xia, Yongzheng Guo   +9 more
wiley   +1 more source

Orthostatic intolerance in chronic fatigue syndrome

Journal of Translational Medicine, 2019
Background Orthostatic intolerance (OI) is a significant problem for those with chronic fatigue syndrome (CFS). We aimed to characterize orthostatic intolerance in CFS and to study the effects of exercise on OI.
Richard Garner, James N. Baraniuk
doaj   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

Advanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr., Georgii B. Telegin, Aleksandr S. Chernov, Anna A. Kudriaeva, Alexey N. Minakov, Maksim V. Rodionov, Vitaly A. Kazakov, Viktor A. Palikov, Yuri M. Poluektov, Rustam H. Ziganshin, Daria A. Orlova, Alena S. Evpak, Daniil A. Barsuk, Fedor A. Mesheryakov, Aldo Spallone, Dmitry S. Asyutin, Igor N. Pronin, Nikolay A. Konovalov, Dmitri Yu Usachev, Alexander G. Gabibov, Alexander N. Konovalov   +20 more
wiley   +1 more source