Results 181 to 190 of about 1,276,748 (319)

The Irritable Bowel Syndrome [PDF]

, 2009
A 45 year old businessman presents at your clinic with a 2 year history of recurrent abdominal pain, associated with frequent bouts of diarrhoea. The pain is relieved by defaecation, but there is often a feeling of incomplete evacuation.
Zammit, Edward
core  

Systematic Review and Meta‐Analysis of Mismatch Negativity in Autism: Insights Into Predictive Mechanisms

Autism Research, EarlyView.
ABSTRACT Mismatch negativity (MMN) has been frequently used to assess auditory processing and change detection in autism spectrum disorder (ASD), but findings have been fairly inconsistent. To address this issue, we conducted a systematic review and meta‐analysis of MMN amplitude (76 effect sizes) and latency (62 effect sizes) in ASD to identify ...
Laurie‐Anne Sapey‐Triomphe, Romain Bouet, Jérémie Mattout, Sandrine Sonié, Christina Schmitz, Françoise Lecaignard   +5 more
wiley   +1 more source

Debt Intolerance [PDF]

This paper introduces the concept of "debt intolerance," which manifests itself in the extreme duress many emerging market economies experience at levels of indebtedness that would seem manageable by advanced country standards.
Carmen M. Reinhart, Kenneth S. Rogoff, Miguel A. Savastano   +2 more
core  

Exploring Alexithymia, Uncertainty, Anxious Arousal, and Social Anxiety as Mediators of the Relationship Between Sensory Processing Differences and Restricted and Repetitive Behaviors in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Restricted and repetitive behaviors (RRB) are associated with sensory processing (SP) differences for autistic people, and are thought to be a coping strategy to help manage the sensory environment. Previous work shows that, for autistic people, alexithymia, intolerance of uncertainty (IU), and anxiety mediate the relationship between SP ...
Heather L. Moore, Samuel Brice, Natalya Spraggon, Barry Ingham, Mark Freeston, Jeremy R. Parr, Jacqui Rodgers   +6 more
wiley   +1 more source

Cardiopulmonary determinants of reduced exercise tolerance in Fabry disease

Frontiers in Cardiovascular Medicine
Fabry disease (FD), also known as Anderson-Fabry disease, is a hereditary disorder of glycosphingolipid metabolism, caused by a deficiency of the lysosomal alpha-galactosidase A enzyme.
Oriana De Marco, Jessica Gambardella, Jessica Gambardella, Antonio Bianco, Antonella Fiordelisi, Federica Andrea Cerasuolo, Antonietta Buonaiuto, Roberta Avvisato, Ivana Capuano, Maria Amicone, Teodolinda Di Risi, Teodolinda Di Risi, Eleonora Riccio, Letizia Spinelli, Antonio Pisani, Antonio Pisani, Guido Iaccarino, Guido Iaccarino, Daniela Sorriento, Daniela Sorriento   +19 more
doaj   +1 more source

Pharmacogenomics in clinical practice: Biomarker information in Brazilian drug labels

British Journal of Clinical Pharmacology, EarlyView.
This review examines the PGx annotations in package inserts (bulas in Brazilian Portuguese) approved by ANVISA, the Brazilian Health Regulatory Agency, for 19 gene–drug pairs with strong or moderate recommendations for initial dosing alteration in the CPIC (Clinical Pharmacogenetic Implementation Consortion) guidelines and PGx testing required or ...
Guilherme Suarez‐Kurtz
wiley   +1 more source

Impact of body position on hemodynamic measurements during exercise: A tale of two bikes

Pulmonary Circulation
The addition of exercise testing during right heart catheterization (RHC) is often required to accurately diagnose causes of exercise intolerance like early pulmonary vascular disease, occult left heart disease, and preload insufficiency.
Pradhab Kirupaharan, James Lane, Celia Melillo, Deborah Paul, Alla Amoushref, Sami Al Abdi, Adriano R. Tonelli   +6 more
doaj   +1 more source

Comparison of Bronchoalveolar Lavage and Tracheal Aspirate Results in 64 Non‐Thoroughbred Horses Presenting with Respiratory Signs or Exercise Intolerance [PDF]

, 2014
Heli I. Koskinen, Marja Raekallio, Emmi Rahkonen, Minna M. Rajamäki, Anna Mykkänen   +4 more
openalex   +1 more source

Magnetic Resonance-Augmented Cardiopulmonary Exercise Testing Comprehensively Assessing Exercise Intolerance in Children with Cardiovascular Disease [PDF]

, 2016
BACKGROUND: Conventional cardiopulmonary exercise testing can objectively measure exercise intolerance but cannot provide comprehensive evaluation of physiology.
Ako, EO, Barber, NJ, Cheang, MH, Kowalik, GT, Moledina, S, Muthurangu, V, Pandya, B, Steeden, JA   +7 more
core  

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source