Results 11 to 20 of about 53,568 (231)

Reduced Fetuin‐A Levels Are Associated With Exercise Intolerance and Predict the Risk of Adverse Outcomes in Patients With Heart Failure: The Role of Cardiac–Hepatic–Peripheral Interaction [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Exercise intolerance in heart failure arises from multifactorial pathophysiological mechanisms. Hepatokines, liver‐synthesized molecules, regulate systemic metabolisms in peripheral tissues.
Yusuke Tomita, Tomofumi Misaka, Yukiko Sugawara, Yasuhiro Ichijo, Fumiya Anzai, Yu Sato, Yusuke Kimishima, Tetsuro Yokokawa, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Akiomi Yoshihisa, Yasuchika Takeishi   +12 more
doaj   +2 more sources

Autonomic cardiovascular reflex control of hemodynamics during exercise in heart failure with reduced ejection fraction and the effects of exercise training [PDF]

Reviews in Cardiovascular Medicine, 2022
Heart failure with reduced ejection fraction is associated with increased exercise intolerance, morbidity, and mortality. Importantly, exercise intolerance in heart failure with reduced ejection fraction is a key factor limiting patient quality of ...
Natasha G. Boyes, Darcy D. Marciniuk, Haissam Haddad, Corey R. Tomczak   +3 more
doaj   +1 more source

Sympathetic and hemodynamic responses to exercise in heart failure with preserved ejection fraction

Frontiers in Cardiovascular Medicine, 2023
Excessive sympathetic activity during exercise causes heightened peripheral vasoconstriction, which can reduce oxygen delivery to active muscles, resulting in exercise intolerance.
Kazumasa Manabe, Kazumasa Manabe, Andrew W. D’Souza, Andrew W. D’Souza, Andrew W. D’Souza, Takuro Washio, Takuro Washio, Ryosuke Takeda, Ryosuke Takeda, Sarah L. Hissen, Sarah L. Hissen, John D. Akins, John D. Akins, Qi Fu, Qi Fu   +14 more
doaj   +1 more source

Exercise Training Preserves Myocardial Strain and Improves Exercise Tolerance in Doxorubicin-Induced Cardiotoxicity

Frontiers in Cardiovascular Medicine, 2021
Doxorubicin causes cardiotoxicity and exercise intolerance. Pre-conditioning exercise training seems to prevent doxorubicin-induced cardiac damage.
Igor L. Gomes-Santos, Camila P. Jordão, Clevia S. Passos, Patricia C. Brum, Edilamar M. Oliveira, Roger Chammas, Anamaria A. Camargo, Carlos E. Negrão, Carlos E. Negrão   +8 more
doaj   +1 more source

Exercise intolerance in heart failure with preserved ejection fraction: Causes, consequences and the journey towards a cure. [PDF]

Exp Physiol, 2023
Bunsawat K, Nelson MD, Hearon CM, Wray DW.   +3 more
europepmc   +3 more sources

Exercise-induced myocardial ischemia presenting as exercise intolerance after carbon monoxide intoxication and smoke inhalation Injury: case report

BMC Cardiovascular Disorders, 2022
Background Carbon monoxide intoxication and smoke inhalation injury can lead to severe disorders, and the current literature has elaborated on the importance of major cardiopulmonary impairment.
Yu-Mei Wang, Chao-Chun Huang, Kuan-Fu Liu, Chen-Liang Chou, Jen-Ting Lee, Su-Ying Hung, Po-Cheng Hsu   +6 more
doaj   +1 more source

Cancer Therapy and Exercise Intolerance: The Heart Is But a Part: JACC: CardioOncology State-of-the-Art Review. [PDF]

JACC CardioOncol
Dillon HT, Foulkes SJ, Baik AH, Scott JM, Touyz RM, Herrmann J, Haykowsky MJ, La Gerche A, Howden EJ.   +8 more
europepmc   +2 more sources

Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice

Molecular Metabolism, 2022
Objective: Mitochondrial disorders are often characterized by muscle weakness and fatigue. Null mutations in the heart-muscle adenine nucleotide translocator isoform 1 (ANT1) of both humans and mice cause cardiomyopathy and myopathy associated with ...
Patrick M. Schaefer, Jessica Huang, Arrienne Butic, Caroline Perry, Tal Yardeni, Wendy Tan, Ryan Morrow, Joseph A. Baur, Douglas C. Wallace   +8 more
doaj   +1 more source

Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction

Cardiac Failure Review, 2020
Nearly half of patients with heart failure in the community have heart failure with preserved ejection fraction (HFpEF). Patients with HFpEF are often elderly and their primary chronic symptom is severe exercise intolerance.
Hidekatsu Fukuta
doaj   +1 more source

Mitochondria Transplantation: Rescuing Innate Muscle Bioenergetic Impairment in a Model of Aging and Exercise Intolerance. [PDF]

J Strength Cond Res
Arroum T, Hish GA, Burghardt KJ, Ghamloush M, Bazzi B, Mrech A, Morse PT, Britton SL, Koch LG, McCully JD, Hüttemann M, Malek MH.   +11 more
europepmc   +3 more sources