Results 31 to 40 of about 1,276,748 (319)

Hyperventilation: A Possible Explanation for Long-Lasting Exercise Intolerance in Mild COVID-19 Survivors?

Frontiers in Physiology, 2021
Since the outbreak of the coronavirus (COVID-19) pandemic, most attention has focused on containing transmission and addressing the surge of critically ill patients in acute care settings.
J. Motiejunaite, P. Balagny, F. Arnoult, L. Mangin, C. Bancal, M. d’Ortho, J. Frija-Masson   +6 more
semanticscholar   +1 more source

Could SGLT2 Inhibitors Improve Exercise Intolerance in Chronic Heart Failure?

International Journal of Molecular Sciences, 2022
Despite the constant improvement of therapeutical options, heart failure (HF) remains associated with high mortality and morbidity. While new developments in guideline-recommended therapies can prolong survival and postpone HF hospitalizations, impaired ...
S. Voorrips, Huitizilihuitl Saucedo-Orozco, P. Sánchez-Aguilera, Rudolf A. de Boer, P. van der Meer, B. Westenbrink   +5 more
semanticscholar   +1 more source

Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice

Molecular Metabolism, 2022
Objective: Mitochondrial disorders are often characterized by muscle weakness and fatigue. Null mutations in the heart-muscle adenine nucleotide translocator isoform 1 (ANT1) of both humans and mice cause cardiomyopathy and myopathy associated with ...
Patrick M. Schaefer, Jessica Huang, Arrienne Butic, Caroline Perry, Tal Yardeni, Wendy Tan, Ryan Morrow, Joseph A. Baur, Douglas C. Wallace   +8 more
doaj   +1 more source

Ongoing Exercise Intolerance Following COVID‐19: A Magnetic Resonance–Augmented Cardiopulmonary Exercise Test Study

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2022
Background Ongoing exercise intolerance of unclear cause following COVID‐19 infection is well recognized but poorly understood. We investigated exercise capacity in patients previously hospitalized with COVID‐19 with and without self‐reported exercise ...
James T Brown, A. Saigal, N. Karia, R. Patel, Y. Razvi, Natalie Constantinou, J. Steeden, S. Mandal, T. Kotecha, M. Fontana, J. Goldring, V. Muthurangu, D. Knight   +12 more
semanticscholar   +1 more source

Distinguishing exercise intolerance in early‐stage pulmonary hypertension with invasive exercise hemodynamics: Rest V E/VCO2 and ETCO2 identify pulmonary vascular disease

Clinical Cardiology, 2022
Among subjects with exercise intolerance and suspected early‐stage pulmonary hypertension (PH), early identification of pulmonary vascular disease (PVD) with noninvasive methods is essential for prompt PH management.
Farhan Raza, N. Dharmavaram, T. Hess, R. Dhingra, James R. Runo, Amy Chybowski, Callyn J Kozitza, S. Batra, E. Horn, N. Chesler, Marlowe Eldridge   +10 more
semanticscholar   +1 more source

Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction

Cardiac Failure Review, 2020
Nearly half of patients with heart failure in the community have heart failure with preserved ejection fraction (HFpEF). Patients with HFpEF are often elderly and their primary chronic symptom is severe exercise intolerance.
Hidekatsu Fukuta
doaj   +1 more source

Exercise Intolerance in Facioscapulohumeral Muscular Dystrophy

Medicine & Science in Sports & Exercise, 2022
Purpose Determine 1) if adults with facioscapulohumeral muscular dystrophy (FSHD) exhibit exercise intolerance and 2) potential contributing mechanisms to exercise intolerance, specific to FSHD. Methods Eleven people with FSHD (47 ± 13 yr, 4 females) and
Kathryn Vera, M. McConville, Aline Glazos, William Stokes, M. Kyba, Manda L. Keller‐Ross   +5 more
semanticscholar   +1 more source

Fatigue and Exercise Intolerance as Initial Manifestations of a Nonsyndromic Mitochondrial Disorder Due to the Variant m.3243A>G

Case Reports in Neurological Medicine, 2022
Objectives. Fatigue and exercise intolerance have been only rarely reported as initial- and sole-onset manifestations of a mitochondrial disorder (MID).
Josef Finsterer, Sinda Zarrouk
doaj   +1 more source

Recurrent rhabdomyolysis and exercise intolerance: A new phenotype of late-onset thymidine kinase 2 deficiency

Molecular Genetics and Metabolism Reports, 2021
A 29-year-old man developed, since the age of 18, exercise intolerance and exercise-induced rhabdomyolysis, with myoglobinuria. Muscle biopsy showed ragged-red fibers. Multiple mitochondrial DNA deletions were detected. The previously reported pathogenic
Carlos Pablo de Fuenmayor-Fernández de la Hoz, Germán Morís, Cecilia Jiménez-Mallebrera, Carmen Badosa, Aurelio Hernández-Laín, Alberto Blázquez Encinar, Miguel Ángel Martín, Cristina Domínguez-González   +7 more
doaj   +1 more source

Combined use of stress echocardiography and cardiopulmonary exercise testing to assess exercise intolerance in patients treated for acute myocardial infarction.

PLoS ONE, 2021
Exercise intolerance after acute myocardial infarction (AMI) is a predictor of worse prognosis, but its causes are complex and poorly studied. This study assessed the determinants of exercise intolerance using combined stress echocardiography and ...
Krzysztof Smarz, Tomasz Jaxa-Chamiec, Beata Zaborska, Maciej Tysarowski, Andrzej Budaj   +4 more
doaj   +2 more sources